Overview of Retinal Gene Therapy: Current Status and Future Challenges.
Sign Up to like & getrecommendations! Published in 2022 at "Cold Spring Harbor perspectives in medicine"
DOI: 10.1101/cshperspect.a041278
Abstract: The success of the first Food and Drug Administration (FDA)- and European Medicines Agency (EMA)-approved gene therapy for genetic disease, voretigene neparovovec-rzyl, (Luxturna) has helped pave the way for development of retinal gene therapies to… read more here.
Keywords: therapy current; overview retinal; gene therapy; gene ... See more keywords
Novel Targets in Pancreatic Cancer Therapy - Current Status and Ongoing Translational Efforts
Sign Up to like & getrecommendations! Published in 2018 at "Oncology Research and Treatment"
DOI: 10.1159/000493437
Abstract: Pancreatic ductal adenocarcinoma (PDAC, pancreatic cancer) carries one of the poorest overall prognoses of all human malignancies known to date. Despite the introduction of novel therapeutic regimens, the outcome has not markedly improved over the… read more here.
Keywords: therapy current; targets pancreatic; pancreatic cancer; novel targets ... See more keywords
Thrombolytic Therapy in the Current ERA: Myocardial Infarction and Beyond.
Sign Up to like & getrecommendations! Published in 2018 at "Current pharmaceutical design"
DOI: 10.2174/1381612824666171227211623
Abstract: Thrombolytic therapy kick-started the era of modern cardiology but in the last few decades it has been largely supplanted by primary percutaneous coronary intervention (PCI) as the go-to treatment for acute myocardial infarction. However, these… read more here.
Keywords: era; myocardial infarction; therapy current; thrombolytic therapy ... See more keywords
Astatine-211 based radionuclide therapy: Current clinical trial landscape
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2022.1076210
Abstract: Astatine-211 (211At) has physical properties that make it one of the top candidates for use as a radiation source for alpha particle-based radionuclide therapy, also referred to as targeted alpha therapy (TAT). Here, we summarize… read more here.
Keywords: 211 based; therapy current; based radionuclide; current clinical ... See more keywords
Anti-Angiogenic Therapy: Current Challenges and Future Perspectives
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DOI: 10.3390/ijms22073765
Abstract: Anti-angiogenic therapy is an old method to fight cancer that aims to abolish the nutrient and oxygen supply to the tumor cells through the decrease of the vascular network and the avoidance of new blood… read more here.
Keywords: therapy current; angiogenesis; angiogenic therapy; current challenges ... See more keywords
Topical Antimicrobial Therapy: Current Status and Challenges.
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DOI: 10.4103/ijmm.ijmm_19_443
Abstract: Topically applied antibacterial agents are widely used. Opinions regarding the clinical efficacy of topical antibiotics are conflicting, and for most indications, alternative oral therapies are available. Topical application has many potential advantages over systemic therapy… read more here.
Keywords: therapy; topical antimicrobial; drug; current status ... See more keywords