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Published in 2019 at "Current Opinion in Neurology"
DOI: 10.1097/wco.0000000000000660
Abstract: Purpose of review To review the history, pharmacology, and clinical science of cannabidiol (CBD) in the treatment of epilepsy. Recent findings Phase III randomized controlled trials and prospective open label trials have provided efficacy and…
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Keywords:
epilepsy;
cannabinoid therapy;
therapy epilepsy;
pharmacology ... See more keywords
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Published in 2022 at "Science"
DOI: 10.1126/science.ade8836
Abstract: Description On-demand inhibition of neuronal activity reduced spontaneous seizures in mice Epilepsy is the predisposition for spontaneous episodes of synchronous increases in neuronal activity, called seizures. The propensity for seizures can be reduced with antiseizure…
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Keywords:
activity;
therapy epilepsy;
gene therapy;
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Published in 2022 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2022.868531
Abstract: Epilepsy is a chronic non-infectious disease of the brain, characterized primarily by recurrent unprovoked seizures, defined as an episode of disturbance of motor, sensory, autonomic, or mental functions resulting from excessive neuronal discharge. Despite the…
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Keywords:
therapy epilepsy;
gene cell;
cell therapy;
therapy ... See more keywords