Next-generation sequencing-guided molecular-targeted therapy and immunotherapy for biliary tract cancers
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Immunology, Immunotherapy"
DOI: 10.1007/s00262-020-02745-y
Abstract: Chemotherapy is a standard regimen for advanced or relapsed biliary tract cancer (BTC) with a 5-year overall survival (OS) rate of approximately 5% and a median OS of less than a year. Targeted therapies and… read more here.
Keywords: biliary tract; immunotherapy; targeted therapy; therapy ... See more keywords
Efficacy of radiotherapy combined with targeted therapy and immunotherapy for lymph node metastasis of liver cancer
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Cancer Research and Clinical Oncology"
DOI: 10.1007/s00432-025-06182-1
Abstract: To investigate the efficacy and safety of radiotherapy combined with targeted therapy and immunotherapy for liver cancer with lymph node metastasis (LNM). We analysed patients who received radiotherapy for liver cancer with LNM in our… read more here.
Keywords: cancer; therapy immunotherapy; combined targeted; liver cancer ... See more keywords
Hypofractionated radiotherapy combined with targeted therapy or immunotherapy: Dutch survey on current practice, knowledge and challenges
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and Translational Radiation Oncology"
DOI: 10.1016/j.ctro.2022.01.002
Abstract: Highlights • Radiotherapy referral during targeted therapy or immunotherapy occurs regularly.• There is a knowledge gap regarding the implications of combined therapy.• There is no consensus on expected toxicity of combined therapy.• Multidisciplinary protocols regarding… read more here.
Keywords: combined therapy; therapy; therapy immunotherapy; targeted therapy ... See more keywords
Revisiting the role of local treatments in the era of targeted therapy and immunotherapy for hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2025 at "World Journal of Surgical Oncology"
DOI: 10.1186/s12957-025-03963-3
Abstract: The advent of targeted therapy and immunotherapy has revolutionised the management of hepatocellular carcinoma (HCC) patients with all stages, dramatically improving their survival outcomes. Currently, radical resection is still the preferred first-line treatment for early-stage… read more here.
Keywords: therapy; hcc; therapy immunotherapy; local treatments ... See more keywords
ALCHEMIST: Adjuvant targeted therapy or immunotherapy for high-risk resected NSCLC.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.15_suppl.tps9077
Abstract: TPS9077Background: ALCHEMIST (Adjuvant Lung Cancer Enrichment Marker Identification and Sequencing Trial) is a clinical trial platform of the National Cancer Institute that offers biomarker analysi... read more here.
Keywords: alchemist; alchemist adjuvant; targeted therapy; adjuvant targeted ... See more keywords
Lung adenocarcinoma: from molecular basis to genome-guided therapy and immunotherapy.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of thoracic disease"
DOI: 10.21037/jtd.2017.06.20
Abstract: Although adenocarcinoma (ADC) is the most frequent lung cancer, its diagnosis is often late, when the local invasion is important and/or the metastases have already appeared. Therefore, the mortality at 5 years is still very… read more here.
Keywords: therapy immunotherapy; guided therapy; genome guided; lung ... See more keywords
Combining Radiotherapy With Anti-angiogenic Therapy and Immunotherapy; A Therapeutic Triad for Cancer?
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2018.03107
Abstract: Radiotherapy has been used for the treatment of cancer for over a century. Throughout this period, the therapeutic benefit of radiotherapy has continuously progressed due to technical developments and increased insight in the biological mechanisms… read more here.
Keywords: angiogenic therapy; combining radiotherapy; radiotherapy; cancer ... See more keywords
Revisiting targeted therapy and immunotherapy for advanced cholangiocarcinoma
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1142690
Abstract: Cholangiocarcinoma (CCA) is a rare and aggressive type of malignant tumor. In the past few years, there has been an increase in the incidence of CCA. Surgery is the only effective treatment but is only… read more here.
Keywords: cca; cholangiocarcinoma; therapy immunotherapy; targeted therapy ... See more keywords
Molecular Targeted Therapy and Immunotherapy for Myelodysplastic Syndrome
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DOI: 10.3390/ijms221910232
Abstract: Myelodysplastic syndrome (MDS) is a heterogeneous, clonal hematological disorder characterized by ineffective hematopoiesis, cytopenia, morphologic dysplasia, and predisposition to acute myeloid leukemia (AML). Stem cell genomic instability, microenvironmental aberrations, and somatic mutations contribute to leukemic… read more here.
Keywords: therapy immunotherapy; myelodysplastic syndrome; targeted therapy;
Anti-Tumor Effects of Engineered VNP20009-Abvec-Igκ-mPD-1 Strain in Melanoma Mice via Combining the Oncolytic Therapy and Immunotherapy
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14122789
Abstract: Programmed cell death protein 1/Programmed cell death ligand 1 (PD-1/PD-L1) immune checkpoint inhibitors are the most promising treatments for malignant tumors currently, but the low response rate limits their further clinical utilization. To address this… read more here.
Keywords: cell; melanoma mice; therapy immunotherapy; expression ... See more keywords
Lipid metabolism of hepatocellular carcinoma impacts targeted therapy and immunotherapy
Sign Up to like & getrecommendations! Published in 2023 at "World Journal of Gastrointestinal Oncology"
DOI: 10.4251/wjgo.v15.i4.617
Abstract: Hepatocellular carcinoma (HCC) is a common malignant tumor that affecting many people's lives globally. The common risk factors for HCC include being overweight and obese. The liver is the center of lipid metabolism, synthesizing most… read more here.
Keywords: metabolism; lipid metabolism; therapy immunotherapy; targeted therapy ... See more keywords