Perioperative therapy in metastatic colorectal cancer: Pattern of use and survival outcomes
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DOI: 10.1002/jso.26278
Abstract: Multimodality therapy of metastatic colorectal cancer (mCRC) is currently considered the standard of care. The aim of this study was to evaluate the impact of perioperative therapy on surgical resection in mCRC. read more here.
Keywords: therapy metastatic; metastatic colorectal; perioperative therapy; colorectal cancer ... See more keywords
The Emerging Role of Local Therapy in Metastatic Prostate Cancer
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DOI: 10.1007/s11912-020-0868-1
Abstract: Purpose of Review This review summarizes the prospective clinical evidence regarding local therapy in metastatic prostate cancer. Recent Findings The phase 3 STAMPEDE trial showed that prostate radiotherapy confers a survival benefit for newly diagnosed… read more here.
Keywords: prostate; therapy metastatic; local therapy; prostate cancer ... See more keywords
Efficacy and safety of camrelizumab plus apatinib compared to apatinib monotherapy as third‐line or above therapy for metastatic colorectal cancer patients: A retrospective cohort study
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Pharmacy and Therapeutics"
DOI: 10.1111/jcpt.13803
Abstract: Programmed cell death protein‐1 (PD‐1) inhibitors synergize apatinib for anti‐tumour effect by regulating tumour microenvironment, vascular endothelial growth factor, hypoxia condition, immune response, etc. This study aimed to investigate the treatment efficacy and safety of… read more here.
Keywords: line therapy; third line; plus apatinib; safety camrelizumab ... See more keywords
Dual VEGF inhibition with sorafenib and bevacizumab as salvage therapy in metastatic colorectal cancer: results of the phase II North Central Cancer Treatment Group study N054C (Alliance)
Sign Up to like & getrecommendations! Published in 2020 at "Therapeutic Advances in Medical Oncology"
DOI: 10.1177/1758835920910913
Abstract: Background: Bevacizumab (BEV), a monoclonal antibody against vascular endothelial growth factor-A (VEGF-A), is a standard component of medical therapy of metastatic colorectal cancer (mCRC). Activation of alternative angiogenesis pathways has been implicated in resistance to… read more here.
Keywords: therapy metastatic; treatment; salvage therapy; cancer ... See more keywords
Systemic therapy in metastatic pancreatic adenocarcinoma: current practice and perspectives
Sign Up to like & getrecommendations! Published in 2021 at "Therapeutic Advances in Medical Oncology"
DOI: 10.1177/17588359211018539
Abstract: Major breakthroughs have been achieved in the management of metastatic pancreatic ductal adenocarcinoma (PDAC) with FOLFIRINOX (5-fluorouracil + irinotecan + oxaliplatin) and gemcitabine plus nab-paclitaxel approved as a first-line therapy, although the prognosis is still poor. At progression, patients… read more here.
Keywords: therapy metastatic; metastatic pancreatic; systemic therapy; pancreatic adenocarcinoma ... See more keywords
Predictors of first line systemic therapy for metastatic renal cell carcinoma in IMDC favorable risk patients.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.15_suppl.e17086
Abstract: e17086Background: With the induction of molecular targeted agents, which interfere with proteins that play critical roles in tumor growth and progression, and immune checkpoint inhibitors (ICI), th... read more here.
Keywords: predictors first; therapy metastatic; first line; systemic therapy ... See more keywords
Tumor-Targeted Polydopamine-Based Nanoparticles for Multimodal Mapping Following Photothermal Therapy of Metastatic Lymph Nodes
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DOI: 10.2147/ijn.s367975
Abstract: Purpose Lymphadenectomy with lymph node (LN) mapping is essential for surgical removal of solid tumors. Existing agents do not provide accurate multimodal mapping and antitumor therapy for metastatic LNs; therefore, we fabricated a polydopamine (PDA)… read more here.
Keywords: photothermal therapy; multimodal mapping; tumor targeted; therapy metastatic ... See more keywords
Gut Microbiota and Therapy in Metastatic Melanoma: Focus on MAPK Pathway Inhibition
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DOI: 10.3390/ijms231911990
Abstract: Gut microbiome (GM) and its either pro-tumorigenic or anti-tumorigenic role is intriguing and constitutes an evolving landscape in translational oncology. It has been suggested that these microorganisms may be involved in carcinogenesis, cancer treatment response… read more here.
Keywords: gut microbiota; melanoma; therapy; melanoma patients ... See more keywords