Tumor immune microenvironment in therapy‐naive esophageal adenocarcinoma could predict the nodal status
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DOI: 10.1002/cam4.5386
Abstract: Currently, preoperative staging of esophageal adenocarcinoma (EAC) has modest reliability and accuracy for pT and pN stages prediction, which heavily affects overall survival. The interplay among immune checkpoints, oncogenes, and intratumoral and peritumoral immune infiltrating… read more here.
Keywords: therapy naive; immune microenvironment; tumor immune; microenvironment therapy ... See more keywords
Vitamin D and Bone Mineral Density in HIV Newly Diagnosed Therapy-Naive Patients Without Any Secondary Causes of Osteoporosis
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DOI: 10.1007/s00223-018-0474-5
Abstract: Bone loss and vitamin D deficiency are common in HIV patients. However, bone health status in newly diagnosed HIV patients has not been thoroughly described. Our aim was to assess the bone mineral density (BMD),… read more here.
Keywords: newly diagnosed; hiv; bone resorption; bone ... See more keywords
P0115 Selective immune responses to Lachnospiraceae flagellins discriminate therapy-naive pediatric Crohn’s disease patients with distinct host-microbial interaction
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DOI: 10.1093/ecco-jcc/jjae190.0289
Abstract: Pathogenic CD4+ T-cell responses to commensal microbial antigens drive intestinal inflammation in Crohn’s disease (CD). Both hypo- or hyperactive anti-microbial innate immunity could underlie these aberrant T-cell responses. CD patients have increased IgG and T… read more here.
Keywords: igg; therapy naive; responses lachnospiraceae; cell ... See more keywords
Pharmacokinetics and Safety Profile of Artesunate-Amodiaquine Coadministered with Antiretroviral Therapy in Malaria-Uninfected HIV-Positive Malawian Adults
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DOI: 10.1128/aac.00412-18
Abstract: ABSTRACT There are limited data on the pharmacokinetic and safety profiles of artesunate-amodiaquine in human immnunodeficiency virus-infected (HIV+) individuals receiving antiretroviral therapy. In a two-step intensive sampling pharmacokinetic trial, we compared the area under the… read more here.
Keywords: antiretroviral therapy; safety; therapy; artesunate amodiaquine ... See more keywords