Epidemiologic outlook of therapy‐related myeloid neoplasms and selection of high‐risk patients: A Korean nationwide study
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DOI: 10.1002/cncr.34453
Abstract: Although a considerable proportion of patients with cancer receive chemotherapy (CT) or radiotherapy (RT), only a very few patients eventually develop therapy‐related myeloid neoplasms (t‐MNs). read more here.
Keywords: related myeloid; outlook therapy; myeloid neoplasms; therapy related ... See more keywords
Clinical presentation, diagnosis and management of therapy‐related hematological disorders in women with epithelial ovarian cancer treated with chemotherapy and poly‐ADP‐ribose polymerase inhibitors: A single‐center experience
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Cancer"
DOI: 10.1002/ijc.33269
Abstract: We investigated the occurrence and management of therapy‐related hematological disorders (tr‐HDs) in women with epithelial ovarian cancer (EOC) exposed to poly‐ADP‐ribose polymerase inhibitors (PARPi), after previous chemotherapy. We analyzed 130 consecutive EOC patients treated with… read more here.
Keywords: therapy related; hematological disorders; management; cancer ... See more keywords
Molecular targeted therapy-related life-threatening toxicity in patients with malignancies. A systematic review of published cases
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DOI: 10.1007/s00134-019-05650-w
Abstract: BackgroundMolecular targeted therapy increased overall and disease-free survival in a wide range of malignancies. Although generally well tolerated compared to chemotherapy, molecular targeted therapy may be associated with adverse events requiring ICU admission. Informing clinicians… read more here.
Keywords: therapy related; targeted therapy; molecular targeted; life threatening ... See more keywords
Therapy-related myeloid neoplasms following treatment for multiple myeloma—a single center analysis
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DOI: 10.1007/s00277-022-04775-1
Abstract: Myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML) can be late complications following mutagenic treatment. Limited data is available on the outcome of patients developing therapy-related MDS and AML after treatment for multiple myeloma (MM).… read more here.
Keywords: therapy related; mds; myeloma; treatment multiple ... See more keywords
Durable response of therapy-related MDS/AML with concomitant Waldenström’s macroglobulinemia treated with venetoclax and azacitidine
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DOI: 10.1007/s00277-022-04777-z
Abstract: Dear Editor, Venetoclax is an oral drug that is BH3-mimetic and a selective B-cell lymphoma 2 (BCL-2) inhibitor. Inhibition of BCL-2 induces apoptosis in hematological malignancies [1]. Venetoclax has shown activity in patients with acute… read more here.
Keywords: response; therapy related; aml; mds aml ... See more keywords
Cytokeratin expression in therapy-related leukemia
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DOI: 10.1007/s12185-020-03062-x
Abstract: An 86-year-old man presented with blasts in peripheral blood and thrombocytopenia. His medical history included lung cancer and esophageal cancer, which had been detected on PET-CT in the previous year. Esophageal cancer (squamous cell carcinoma,… read more here.
Keywords: cancer; therapy related; expression; related leukemia ... See more keywords
Therapy-related acute lymphoblastic leukemia: Where do we stand with regards to its definition and characterization?
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DOI: 10.1016/j.blre.2019.06.001
Abstract: Acute lymphoblastic leukemia (ALL) arising in patients with prior malignancy is increasingly being reported. Although terms such as 'secondary' and 'therapy-related' have been interchangeably used to characterize these cases of ALL in a similar fashion… read more here.
Keywords: therapy related; cytotoxic therapy; lymphoblastic leukemia; acute lymphoblastic ... See more keywords
3005 – ELIMINATION OF RUNX1 MUTANT PRE-LEUKEMIC CLONES IN THERAPY-RELATED MYELODYSPLASTIC SYNDROME
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DOI: 10.1016/j.exphem.2020.09.027
Abstract: Therapy-related Myelodysplastic Syndrome (t-MDS) accounts for up to 20% of all MDS cases and its prevalence is expected to grow as more cancer patients survive. Unfortunately, the prognosis for t-MDS remains poor with 5-year overall… read more here.
Keywords: related myelodysplastic; elimination runx1; 3005 elimination; myelodysplastic syndrome ... See more keywords
Acute myeloid leukemia with 11q23 rearrangements: A study of therapy-related disease and therapeutic outcomes.
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DOI: 10.1016/j.leukres.2020.106453
Abstract: We described the clinical features and outcomes for 63 adult patients with acute myeloid leukemia (AML) with a translocation involving the 11q23 locus (MLL) who were treated at Memorial Sloan Kettering Cancer Center (MSK). The… read more here.
Keywords: therapy related; related disease; myeloid leukemia; disease ... See more keywords
A case of therapy-related acute lymphoblastic leukemia following the treatment of acute myeloid leukemia
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DOI: 10.1016/j.lrr.2022.100297
Abstract: Therapy-related acute lymphoblastic leukemia represents a distinct entity associated with inferior survival compared with de novo acute lymphoblastic leukemia. It consists of a subset of patients who have had exposure to chemotherapy or radiation for… read more here.
Keywords: therapy related; leukemia; acute lymphoblastic; related acute ... See more keywords
Therapy-related myeloid neoplasm in an 18-year-old boy with B-lymphoblastic leukemia.
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DOI: 10.1016/j.yexmp.2017.11.007
Abstract: BACKGROUND Acute lymphoblastic leukemia (ALL) is the most common pediatric malignancy. Acute myeloid leukemia or myelodysplastic syndrome during the course of ALL is a rare entity. Some of these cases are therapy-related while the others… read more here.
Keywords: therapy related; diagnosis; myeloid neoplasm; lymphoblastic leukemia ... See more keywords