Live attenuated bacterium limits cancer resistance to CAR-T therapy by remodeling the tumor microenvironment
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DOI: 10.1136/jitc-2021-003760
Abstract: The tumor microenvironment (TME) is characterized by the activation of immune checkpoints, which limit the ability of immune cells to attack the growing cancer. To overcome immune suppression in the clinic, antigen-expressing viruses and bacteria… read more here.
Keywords: therapy remodeling; tumor microenvironment; live attenuated; cancer resistance ... See more keywords