The use of molecular volumetric parameters for the evaluation of Lu-177 PSMA I&T therapy response and survival
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Nuclear Medicine"
DOI: 10.1007/s12149-019-01376-3
Abstract: The primary aim of this study was to evaluate the volumetric therapy response via Ga-68 PSMA I&T PET/CT in patients treated with Lu-177 PSMA I&T therapy. The secondary purpose was to determine the impact of… read more here.
Keywords: response; therapy response; 177 psma; therapy ... See more keywords
Molecular Imaging and Precision Medicine: PET/Computed Tomography and Therapy Response Assessment in Oncology.
Sign Up to like & getrecommendations! Published in 2017 at "PET clinics"
DOI: 10.1016/j.cpet.2016.08.002
Abstract: A variety of methods have been developed to assess tumor response to therapy. Standardized qualitative criteria based on 18F-fluoro-deoxyglucose PET/computed tomography have been proposed to evaluate the treatment effectiveness in specific cancers and these allow… read more here.
Keywords: medicine; oncology; therapy response; response assessment ... See more keywords
Bladder cancer organoids as a functional system to model different disease stages and therapy response
Sign Up to like & getrecommendations! Published in 2022 at "Nature Communications"
DOI: 10.1101/2022.03.31.486514
Abstract: Bladder Cancer (BLCa) inter-patient heterogeneity is the primary cause of treatment failure, suggesting that patients could benefit from a more personalized treatment approach. Patient-derived organoids (PDOs) have been successfully used as a functional model for… read more here.
Keywords: drug; bladder cancer; response; therapy response ... See more keywords
Cancer organoids to model therapy response
Sign Up to like & getrecommendations! Published in 2018 at "Science"
DOI: 10.1126/science.359.6378.880-d
Abstract: Organoids Cancer organoids are miniature, three-dimensional cell culture models that can be made from primary patient tumors and studied in the laboratory. Vlachogiannis et al. asked whether such “tumor-in-a-dish” approaches can be used to predict… read more here.
Keywords: drug; therapy response; cancer organoids; model therapy ... See more keywords
Abstract IA07: Genetic determinants of tumor development, therapy response and resistance in mouse models of BRCA-deficient breast cancer
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Cancer Research"
DOI: 10.1158/1557-3125.dnarepair16-ia07
Abstract: Heterozygous germline mutations in BRCA1 or BRCA2 strongly predispose to development of breast and ovarian cancer (as well as other cancer types) via loss of the remaining wildtype allele. BRCA1/2-deficient cancers are defective in DNA… read more here.
Keywords: breast; therapy response; resistance; cancer ... See more keywords
Therapy Response and Outcome Explained by Leukemia Cell of Origin.
Sign Up to like & getrecommendations! Published in 2020 at "Cancer discovery"
DOI: 10.1158/2159-8290.cd-20-1080
Abstract: In this issue of Cancer Discovery, Cai and colleagues delineate a new mechanism that links cell of origin, the transcription factor EVI1, apoptotic priming, and therapeutic susceptibility in mixed lineage leukemia-rearranged acute myeloid leukemia. These… read more here.
Keywords: cell origin; leukemia; outcome explained; therapy response ... See more keywords
Prediction of radiation therapy response in breast cancer patients.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2017.35.15_suppl.565
Abstract: 565Background: While radiation portals are tailored to a patient’s unique anatomy and the selection of systemic agents routinely employs biomarker data, the selection of radiotherapy based on a pat... read more here.
Keywords: radiation therapy; prediction radiation; breast cancer; therapy response ... See more keywords
Superior therapy response predictions for patients with low-grade glioma (LGG) using Cellworks Singula: MyCare-009-04.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.15_suppl.2569
Abstract: 2569Background: Despite using cytogenetic and molecular-risk stratification and precision medicine, the current overall outcome of LGG patients remains relatively poor. Therapy selection is often b... read more here.
Keywords: lgg; superior therapy; predictions patients; therapy response ... See more keywords
AGR2 expression as a predictive biomarker for therapy response in esophageal squamous cell carcinoma
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DOI: 10.1371/journal.pone.0276990
Abstract: Despite multidisciplinary therapy, the prognosis is poor for esophageal squamous cell carcinoma (ESCC). In the locally advanced stage, neoadjuvant chemoradiotherapy (nCRT) followed by surgery could provide survival benefits to some patients. Here, we aimed to… read more here.
Keywords: therapy response; squamous cell; therapy; esophageal squamous ... See more keywords
Novel genetic alterations and their impact on target therapy response in head and neck squamous cell carcinoma
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DOI: 10.2147/cmar.s187780
Abstract: Head and neck squamous cell carcinoma (HNSCC) is highly variable by tumor site, histologic type, molecular characteristics, and clinical outcome. During recent years, emerging targeted therapies have been focused on driver genes. HNSCC involves several… read more here.
Keywords: therapy response; genetic alterations; neck squamous; head neck ... See more keywords
Correlation of Iodine Quantification and FDG Uptake in Early Therapy Response Assessment of Non-small Cell Lung Cancer: Possible Benefit of Dual-energy CT Scan as an Integral Part of PET/CT Examination
Sign Up to like & getrecommendations! Published in 2020 at "AntiCancer Research"
DOI: 10.21873/anticanres.14332
Abstract: Aim: To compare iodine-related and fluorine-18 fluorodeoxyglucose (18F-FDG) parameters during staging of lung cancer as well as during early follow-up, while investigating potential use and possible substitutability in the assessment of therapeutic response or prediction.… read more here.
Keywords: correlation; therapy response; response; lung cancer ... See more keywords