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Published in 2017 at "Immunology and Cell Biology"
DOI: 10.1038/icb.2016.128
Abstract: The potential for immunotherapy as a treatment option for cancer is clear from remarkable responses of some leukemia patients to adoptive cell transfer using autologous T cells genetically modified to express chimeric antigen receptors (CARs).…
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Keywords:
car cell;
cell therapy;
therapy solid;
cell ... See more keywords
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Published in 2022 at "Cancer Investigation"
DOI: 10.1080/07357907.2022.2125004
Abstract: Abstract This systematic review aims to assess all the prospective studies published to date on the efficacy of CAR-T cell therapy in solid tumors. Databases searched were PubMed and Google Scholar from inception through May…
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Keywords:
cell;
cell therapy;
systematic review;
car ... See more keywords
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Published in 2021 at "American Journal of Transplantation"
DOI: 10.1111/ajt.16836
Abstract: Our understanding of the involvement of the gut microbiota (GM) in human health has expanded exponentially over the last few decades, particularly in the fields of metabolism, inflammation, and immunology. Immunosuppressive treatment (IST) prescribed to…
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Keywords:
immunosuppressive therapy;
therapy solid;
solid organ;
transplantation ... See more keywords
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3
Published in 2023 at "Science Advances"
DOI: 10.1126/sciadv.adf3700
Abstract: T cell engineering has changed the landscape of cancer immunotherapy. Chimeric antigen receptor T cells have demonstrated a remarkable efficacy in the treatment of B cell malignancies in hematology. However, their clinical impact on solid…
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Keywords:
engineered cell;
cell;
cell therapy;
therapy solid ... See more keywords
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Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.849759
Abstract: Chimeric antigen receptor T cell (CAR-T) therapy for the treatment of hematologic tumors has achieved remarkable success, with five CAR-T therapies approved by the United States Food and Drug Administration. However, the efficacy of CAR-T…
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Keywords:
car therapy;
nanotechnology;
car;
therapy solid ... See more keywords
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2
Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1045024
Abstract: Chimeric antigen receptor (CAR) T cells therapy has emerged as a significant breakthrough in adoptive immunotherapy for hematological malignancies with FDA approval. However, the application of CAR-T cell therapy in solid tumors remains challenging, mostly…
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Keywords:
cell therapy;
car;
therapy solid;
solid tumors ... See more keywords