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   Articles with "therapy solid" as a keyword



Immuno-Packed T-Cell-Fusogenic Liposome Empowers Adoptive T Cell Therapy for Solid Tumor Treatment.

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recommendations! Published in 2025 at "Advanced materials"

DOI: 10.1002/adma.202510842

Abstract: Adoptive T cell therapy has achieved remarkable success in certain blood cancers, but its efficacy against solid tumors remains limited by multiple immunological challenges including inadequate tumor infiltration, tumor cell's immune tolerance, and immunosuppressive tumor microenvironment… read more here.

Keywords: cell therapy; cell; tumor; therapy solid ... See more keywords

CAR T‐cell therapy of solid tumors

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recommendations! Published in 2017 at "Immunology and Cell Biology"

DOI: 10.1038/icb.2016.128

Abstract: The potential for immunotherapy as a treatment option for cancer is clear from remarkable responses of some leukemia patients to adoptive cell transfer using autologous T cells genetically modified to express chimeric antigen receptors (CARs).… read more here.

Keywords: car cell; cell therapy; therapy solid; cell ... See more keywords

CAR-T Cell Therapy for Solid Tumors: Are we Still That Far? a Systematic Review of Literature

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recommendations! Published in 2022 at "Cancer Investigation"

DOI: 10.1080/07357907.2022.2125004

Abstract: Abstract This systematic review aims to assess all the prospective studies published to date on the efficacy of CAR-T cell therapy in solid tumors. Databases searched were PubMed and Google Scholar from inception through May… read more here.

Keywords: cell; cell therapy; systematic review; car ... See more keywords

Immunosuppressive therapy after solid organ transplantation and the gut microbiota: Bidirectional interactions with clinical consequences

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recommendations! Published in 2021 at "American Journal of Transplantation"

DOI: 10.1111/ajt.16836

Abstract: Our understanding of the involvement of the gut microbiota (GM) in human health has expanded exponentially over the last few decades, particularly in the fields of metabolism, inflammation, and immunology. Immunosuppressive treatment (IST) prescribed to… read more here.

Keywords: immunosuppressive therapy; therapy solid; solid organ; transplantation ... See more keywords

TCR-engineered T cell therapy in solid tumors: State of the art and perspectives

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recommendations! Published in 2023 at "Science Advances"

DOI: 10.1126/sciadv.adf3700

Abstract: T cell engineering has changed the landscape of cancer immunotherapy. Chimeric antigen receptor T cells have demonstrated a remarkable efficacy in the treatment of B cell malignancies in hematology. However, their clinical impact on solid… read more here.

Keywords: engineered cell; cell; cell therapy; therapy solid ... See more keywords

Elevating the potential of CAR-T cell therapy in solid tumors: exploiting biomaterials-based delivery techniques

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recommendations! Published in 2024 at "Frontiers in Bioengineering and Biotechnology"

DOI: 10.3389/fbioe.2023.1320807

Abstract: Chimeric antigen receptor (CAR) T cells exhibit promising progress in addressing hematologic malignancies. However, CAR-T therapy for solid tumors remains limited, with no FDA-approved CAR-T products available for clinical use at present. Primary reasons include… read more here.

Keywords: therapy solid; car; solid tumors; car cell ... See more keywords

Advances in Nanotechnology Development to Overcome Current Roadblocks in CAR-T Therapy for Solid Tumors

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recommendations! Published in 2022 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2022.849759

Abstract: Chimeric antigen receptor T cell (CAR-T) therapy for the treatment of hematologic tumors has achieved remarkable success, with five CAR-T therapies approved by the United States Food and Drug Administration. However, the efficacy of CAR-T… read more here.

Keywords: car therapy; nanotechnology; car; therapy solid ... See more keywords

Bright future or blind alley? CAR-T cell therapy for solid tumors

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recommendations! Published in 2023 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2023.1045024

Abstract: Chimeric antigen receptor (CAR) T cells therapy has emerged as a significant breakthrough in adoptive immunotherapy for hematological malignancies with FDA approval. However, the application of CAR-T cell therapy in solid tumors remains challenging, mostly… read more here.

Keywords: cell therapy; car; therapy solid; solid tumors ... See more keywords