Articles with "therapy targeting" as a keyword



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Effects of SlowMo, a Blended Digital Therapy Targeting Reasoning, on Paranoia Among People With Psychosis

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Published in 2021 at "JAMA Psychiatry"

DOI: 10.1001/jamapsychiatry.2021.0326

Abstract: Key Points Question Can a brief blended digital therapy targeting reasoning (SlowMo) improve paranoia for adults with psychosis when added to usual care? Findings This randomized clinical trial of 361 individuals with clinical paranoia did… read more here.

Keywords: paranoia; targeting reasoning; blended digital; therapy ... See more keywords

New avenues for NASH therapy by targeting ACC.

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Published in 2022 at "Cell metabolism"

DOI: 10.1016/j.cmet.2022.01.001

Abstract: Acetyl-CoA carboxylase (ACC) is one of the more promising therapeutic targets for non-alcoholic steatohepatitis (NASH), but current ACC inhibitors already tested in clinical trials also exert the unwanted adverse side effect of hypertriglyceridemia. In two… read more here.

Keywords: medicine; avenues nash; nash therapy; new avenues ... See more keywords
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Targeting TGFβ signal transduction for cancer therapy

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Published in 2021 at "Signal Transduction and Targeted Therapy"

DOI: 10.1038/s41392-020-00436-9

Abstract: Transforming growth factor-β (TGFβ) family members are structurally and functionally related cytokines that have diverse effects on the regulation of cell fate during embryonic development and in the maintenance of adult tissue homeostasis. Dysregulation of… read more here.

Keywords: therapy; targeting tgf; cancer; signal transduction ... See more keywords

Testosterone recovery therapy targeting dysfunctional Leydig cells.

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Published in 2022 at "Andrology"

DOI: 10.1111/andr.13304

Abstract: INTRODUCTION Erectile dysfunction (ED) is associated with diabetes mellitus with an estimated prevalence of 52.5% in the diabetic population. The first-line therapy for ED are phosphodiesterase type 5 inhibitors (PDE5i), but data suggests that diabetic… read more here.

Keywords: testosterone recovery; diabetic men; therapy; recovery therapy ... See more keywords

Novel cancer therapy targeting microbiome

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Published in 2019 at "OncoTargets and therapy"

DOI: 10.2147/ott.s207546

Abstract: Abstract In the human intestinal tract, there are more than 100 trillion symbiotic bacteria, which form the gut microbiota. Approximately 70% of the human immune system is in the intestinal tract, which prevents infection by… read more here.

Keywords: microbiota; cancer; cancer therapy; therapy targeting ... See more keywords
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Intramuscular Delivery of Gene Therapy for Targeting the Nervous System

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Published in 2020 at "Frontiers in Molecular Neuroscience"

DOI: 10.3389/fnmol.2020.00129

Abstract: Virus-mediated gene therapy has the potential to deliver exogenous genetic material into specific cell types to promote survival and counteract disease. This is particularly enticing for neuronal conditions, as the nervous system is renowned for… read more here.

Keywords: nervous system; delivery; gene therapy; gene ... See more keywords

Preclinical Photodynamic Therapy Targeting Blood Vessels with AGuIX® Theranostic Nanoparticles

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Published in 2024 at "Cancers"

DOI: 10.3390/cancers16233924

Abstract: Simple Summary Glioblastoma multiforme is the most common primary malignant brain tumor and is usually fatal shortly after diagnosis due to its rapid growth and aggressive nature. Improved drug delivery technologies such as nanoparticles are… read more here.

Keywords: targeting blood; preclinical photodynamic; therapy targeting; glioblastoma multiforme ... See more keywords

Adoptive T Cell Therapy Targeting MAGE-A4

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Published in 2025 at "Cancers"

DOI: 10.3390/cancers17030413

Abstract: Simple Summary MAGE A4 is a protein found in several types of cancer, but not usually in healthy tissues. This makes it a good target for therapies that aim to destroy cancer cells while leaving… read more here.

Keywords: cell therapy; therapy; mage; therapy targeting ... See more keywords