Effects of SlowMo, a Blended Digital Therapy Targeting Reasoning, on Paranoia Among People With Psychosis
Sign Up to like & getrecommendations! Published in 2021 at "JAMA Psychiatry"
DOI: 10.1001/jamapsychiatry.2021.0326
Abstract: Key Points Question Can a brief blended digital therapy targeting reasoning (SlowMo) improve paranoia for adults with psychosis when added to usual care? Findings This randomized clinical trial of 361 individuals with clinical paranoia did… read more here.
Keywords: paranoia; targeting reasoning; blended digital; therapy ... See more keywords
New avenues for NASH therapy by targeting ACC.
Sign Up to like & getrecommendations! Published in 2022 at "Cell metabolism"
DOI: 10.1016/j.cmet.2022.01.001
Abstract: Acetyl-CoA carboxylase (ACC) is one of the more promising therapeutic targets for non-alcoholic steatohepatitis (NASH), but current ACC inhibitors already tested in clinical trials also exert the unwanted adverse side effect of hypertriglyceridemia. In two… read more here.
Keywords: medicine; avenues nash; nash therapy; new avenues ... See more keywords
Targeting TGFβ signal transduction for cancer therapy
Sign Up to like & getrecommendations! Published in 2021 at "Signal Transduction and Targeted Therapy"
DOI: 10.1038/s41392-020-00436-9
Abstract: Transforming growth factor-β (TGFβ) family members are structurally and functionally related cytokines that have diverse effects on the regulation of cell fate during embryonic development and in the maintenance of adult tissue homeostasis. Dysregulation of… read more here.
Keywords: therapy; targeting tgf; cancer; signal transduction ... See more keywords
Testosterone recovery therapy targeting dysfunctional Leydig cells.
Sign Up to like & getrecommendations! Published in 2022 at "Andrology"
DOI: 10.1111/andr.13304
Abstract: INTRODUCTION Erectile dysfunction (ED) is associated with diabetes mellitus with an estimated prevalence of 52.5% in the diabetic population. The first-line therapy for ED are phosphodiesterase type 5 inhibitors (PDE5i), but data suggests that diabetic… read more here.
Keywords: testosterone recovery; diabetic men; therapy; recovery therapy ... See more keywords
Novel cancer therapy targeting microbiome
Sign Up to like & getrecommendations! Published in 2019 at "OncoTargets and therapy"
DOI: 10.2147/ott.s207546
Abstract: Abstract In the human intestinal tract, there are more than 100 trillion symbiotic bacteria, which form the gut microbiota. Approximately 70% of the human immune system is in the intestinal tract, which prevents infection by… read more here.
Keywords: microbiota; cancer; cancer therapy; therapy targeting ... See more keywords
Intramuscular Delivery of Gene Therapy for Targeting the Nervous System
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2020.00129
Abstract: Virus-mediated gene therapy has the potential to deliver exogenous genetic material into specific cell types to promote survival and counteract disease. This is particularly enticing for neuronal conditions, as the nervous system is renowned for… read more here.
Keywords: nervous system; delivery; gene therapy; gene ... See more keywords