Sustained release buprenorphine effectively attenuates postoperative hypersensitivity in an incisional pain model in neonatal rats (Rattus norvegicus).
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DOI: 10.1371/journal.pone.0246213
Abstract: Despite the need for safe and effective postoperative analgesia in neonates, research regarding pain management in neonatal rodents is relatively limited. Here, we investigate whether sustained release buprenorphine (Bup SR) effectively attenuates thermal hypersensitivity in… read more here.
Keywords: effectively attenuates; thermal hypersensitivity; release buprenorphine; sustained release ... See more keywords
Effectiveness of two extended-release buprenorphine formulations during postoperative period in neonatal rats
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DOI: 10.1371/journal.pone.0276327
Abstract: Information on the effectiveness of a new long-lasting buprenorphine formulation, extended-release buprenorphine, in the neonatal rat is very limited. This study compares whether a high dose of extended-release buprenorphine (XR-Hi) attenuates thermal hypersensitivity for a… read more here.
Keywords: period; thermal hypersensitivity; buprenorphine; extended release ... See more keywords