Structural Dynamics of a Thermally Stressed Monoclonal Antibody Characterized by Temperature-Dependent H/D Exchange Mass Spectrometry.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c03931
Abstract: Differential scanning calorimetry (DSC) is a standard tool for probing the resilience of monoclonal antibodies (mAbs) and other protein therapeutics against thermal degradation. Unfortunately, DSC usually only provides insights into global unfolding, although sequential steps… read more here.
Keywords: temperature dependent; dynamics thermally; mass spectrometry; thermally stressed ... See more keywords
Comparative transcriptomic analysis of thermally stressed Arabidopsis thaliana meiotic recombination mutants
Sign Up to like & getrecommendations! Published in 2021 at "BMC Genomics"
DOI: 10.1186/s12864-021-07497-2
Abstract: Background Meiosis is a specialized cell division that underpins sexual reproduction in most eukaryotes. During meiosis, interhomolog meiotic recombination facilitates accurate chromosome segregation and generates genetic diversity by shuffling parental alleles in the gametes. The… read more here.
Keywords: meiosis; transcriptomic analysis; meiotic recombination; type ... See more keywords