Role of thermogenic adipose tissue in lipid metabolism and atherosclerotic cardiovascular disease: lessons from studies in mice and humans
Sign Up to like & getrecommendations! Published in 2022 at "Cardiovascular Research"
DOI: 10.1093/cvr/cvac131
Abstract: Abstract Brown adipocytes within brown adipose tissue (BAT) and beige adipocytes within white adipose tissue dissipate nutritional energy as heat. Studies in mice have shown that activation of thermogenesis in brown and beige adipocytes enhances… read more here.
Keywords: role; studies mice; thermogenic adipose; adipose tissue ... See more keywords
Developmental and functional heterogeneity of thermogenic adipose tissue
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Molecular Cell Biology"
DOI: 10.1093/jmcb/mjaa029
Abstract: Abstract The obesity epidemic continues to rise as a global health challenge. Thermogenic brown and beige adipocytes dissipate chemical energy as heat, providing an opportunity for developing new therapeutics for obesity and related metabolic diseases.… read more here.
Keywords: thermogenic adipose; functional heterogeneity; tissue; heterogeneity thermogenic ... See more keywords
Thermogenic adipose tissue aging: Mechanisms and implications
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DOI: 10.3389/fcell.2022.955612
Abstract: Adipose tissue undergoes significant anatomical and functional changes with aging, leading to an increased risk of metabolic diseases. Age-related changes in adipose tissue include overall defective adipogenesis, dysfunctional adipokine secretion, inflammation, and impaired ability to… read more here.
Keywords: beige adipocytes; aging mechanisms; thermogenic adipose; adipose tissue ... See more keywords
A neurogenic signature involving monoamine Oxidase-A controls human thermogenic adipose tissue development
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.7554/elife.78945
Abstract: Mechanisms that control “beige/brite” thermogenic adipose tissue development may be harnessed to improve human metabolic health. To define these mechanisms, we developed a species-hybrid model in which human mesenchymal progenitor cells were used to develop… read more here.
Keywords: tissue development; thermogenic adipose; adipose tissue; neurogenic signature ... See more keywords