Engineering of the thermophilic nitrile hydratase from Pseudonocardia thermophila JCM3095 for large-scale nicotinamide production based on sequence-activity relationships.
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DOI: 10.1016/j.ijbiomac.2021.09.132
Abstract: The green biocatalyst nitrile hydratase (NHase) is able to bio-transform 3-cyanopyridine into nicotinamide. As the NHase reaction is exothermic, an enzyme with high activity and stability is needed for nicotinamide production. In this study, we… read more here.
Keywords: production; pseudonocardia thermophila; nitrile hydratase; nicotinamide production ... See more keywords