Biocatalytic synthesis of seleno-, thio- and chloro-nucleobase modified nucleosides by thermostable nucleoside phosphorylases
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DOI: 10.1016/j.catcom.2018.12.004
Abstract: Abstract Selenium-containing nucleosides are the building blocks of the Se-nucleic acids useful for structure-and-function study, drug discovery and for targeting nucleic acids and their protein complexes. However, chemical synthesis of these Se-containing nucleosides is labor-intensive… read more here.
Keywords: modified nucleosides; biocatalytic synthesis; synthesis; thermostable nucleoside ... See more keywords