Ultra-thermostable RNA nanoparticles for solubilizing and high-yield loading of paclitaxel for breast cancer therapy
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DOI: 10.1038/s41467-020-14780-5
Abstract: Paclitaxel is widely used in cancer treatments, but poor water-solubility and toxicity raise serious concerns. Here we report an RNA four-way junction nanoparticle with ultra-thermodynamic stability to solubilize and load paclitaxel for targeted cancer therapy.… read more here.
Keywords: thermostable rna; rna nanoparticles; cancer; cancer therapy ... See more keywords