Small Molecules Targeting DNA Polymerase Theta (POLθ) as Promising Synthetic Lethal Agents for Precision Cancer Therapy
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DOI: 10.1021/acs.jmedchem.2c02101
Abstract: Synthetic lethality (SL) is an innovative strategy in targeted anticancer therapy that exploits tumor genetic vulnerabilities. This topic has come to the forefront in recent years, as witnessed by the increased number of publications since… read more here.
Keywords: polymerase; dna polymerase; polymerase theta; therapy ... See more keywords