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Published in 2020 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2020.112145
Abstract: Morphine and its derivatives play inevitably important role in the μ-opioid receptor (MOR) targeted antinociception. A structure-activity relationship study is presented for novel and known orvinol and thevinol derivatives with varying 3-O, 6-O, 17-N and…
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Keywords:
orvinol thevinol;
synthesis biochemical;
thevinol derivatives;
biochemical pharmacological ... See more keywords