Metabolism of a new synthetic opioid tetrahydrofuranylfentanyl in fresh isolated human hepatocytes: detection and confirmation of ring-opened metabolites.
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DOI: 10.1002/dta.2743
Abstract: The metabolism of a new synthetic opioid tetrahydrofuranylfentanyl (THF-fentanyl) was investigated using fresh human hepatocytes. Fourteen metabolites of THF-fentanyl, such as tetrahydrofuran ring-opened metabolites, desphenethylated metabolites, hydroxylated metabolites, and hydroxylated and methoxylated metabolites and their… read more here.
Keywords: thf fentanyl; metabolism new; ring; ring opened ... See more keywords