Direct radical sulfonylation at α-C(sp3)-H of THF with sodium sulfinates in aqueous medium
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DOI: 10.1016/j.tetlet.2019.02.021
Abstract: Abstract A direct transition-metal-free, convenient and highly regioselective synthesis of 2-alkyl/aryl sulfonyl tetrahydrofurans (THFs) has been achieved from THF and sodium sulfinates using K2S2O8 as a mild oxidant. This one-pot simple protocol involves an efficient… read more here.
Keywords: sodium sulfinates; aqueous medium; direct radical; thf sodium ... See more keywords