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Published in 2017 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2017.06.057
Abstract: Abstract Aromatic diamides, derivative of 2,6-pyridinedicarboxylic acid and isophthalic acid, bearing 1,3,4-thiadiazole residue were prepared with satisfactory yields in conventional procedures and microwave stimulated reactions. X-ray structure of N,N′-bis(1,3,4-thiadiazol-2-yl)-2,6-pyridinedicarboxamide (2) DMSO solvate (2·DMSO) was described.…
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Keywords:
complexation properties;
diamides synthesis;
based diamides;
synthesis complexation ... See more keywords
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Published in 2019 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2018.11.072
Abstract: Abstract A series of thiadiazole-based dithiafulvalene (DTF) derivatives has been synthesized in moderate yields via iodine-mediated oxidative vinylic C(sp2)–H sulfenylation with mercapto-thiadiazoles. The formation of C(sp2)–S bond was confirmed and characterized by NMR and single…
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Keywords:
iodine mediated;
based dithiafulvalene;
elemental iodine;
thiadiazole based ... See more keywords
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Published in 2017 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.7b10256
Abstract: We report a regioregular bis-pyridal[2,1,3]-thiadiazole (BPT) acceptor strategy to construct the first ambipolar pyridal[2,1,3]thiadiazole-based semiconducting polymer (PBPTV). The use of BPT unit enables PBPTV to achieve high electron affinity, low LUMO level, and extended π-conjugation.…
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Keywords:
bis pyridal;
regioregular bis;
thiadiazole based;
based semiconducting ... See more keywords
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Published in 2020 at "Polymer Chemistry"
DOI: 10.1039/c9py01137d
Abstract: A pyridazine thiadiazole acceptor (PzT) has been utilised in the synthesis of a novel low band-gap D–A copolymer PTTPz. It is a much stronger acceptor in comparison to BT and PyT moieties widely incorporated in…
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Keywords:
novel low;
thiadiazole based;
low bandgap;
pyridazine thiadiazole ... See more keywords
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Published in 2021 at "New Journal of Chemistry"
DOI: 10.1039/d0nj05644h
Abstract: Five new multicomponent solid forms of the biologically active 1,2,4-thiadiazole derivative (TDZH) with dicarboxylic and hydroxybenzoic acids have been discovered by combined virtual/experimental cocrystal screening. The interplay between the intrinsic hierarchy of the donor/acceptor groups…
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Keywords:
neuroprotector carboxylic;
thiadiazole based;
cocrystals potent;
based neuroprotector ... See more keywords
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Published in 2022 at "Antibiotics"
DOI: 10.3390/antibiotics11050562
Abstract: Fifteen 4-methyl-1,2,3-thiadiazole-based hydrazone derivatives 3a–d and sulfonyl hydrazones 5a–k were synthesized. They were characterized by 1H-NMR, 13C NMR, and HRMS. Mycobacterium tuberculosis strain H37Rv was used to assess their antimycobacterial activity. All compounds demonstrated significant…
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Keywords:
thiadiazole based;
based hydrazone;
hydrazone derivatives;
methyl thiadiazole ... See more keywords
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Published in 2022 at "Molecules"
DOI: 10.3390/molecules27113613
Abstract: Novel 1,3,4-thiadiazole derivatives were synthesized through the reaction of methyl 2-(4-hydroxy-3-methoxybenzylidene) hydrazine-1-carbodithioate and the appropriate hydrazonoyl halides in the presence of a few drops of diisopropylethylamine. The chemical structure of the newly fabricated compounds was…
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Keywords:
molecular docking;
thiadiazole based;
molecules promising;
based molecules ... See more keywords
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Published in 2022 at "Pharmaceuticals"
DOI: 10.3390/ph15121476
Abstract: A new series of 5-(4-chlorophenyl)-1,3,4-thiadiazole-based compounds featuring pyridinium (3), substituted piperazines (4a–g), benzyl piperidine (4i), and aryl aminothiazoles (5a–e) heterocycles were synthesized. Evaluation of the cytotoxicity potential of the new compounds against MCF-7 and HepG2…
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Keywords:
thiadiazole based;
evaluation;
radioactive tracing;
new aryl ... See more keywords