1,3,4-Thiadiazole-based diamides: Synthesis and complexation properties
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2017.06.057
Abstract: Abstract Aromatic diamides, derivative of 2,6-pyridinedicarboxylic acid and isophthalic acid, bearing 1,3,4-thiadiazole residue were prepared with satisfactory yields in conventional procedures and microwave stimulated reactions. X-ray structure of N,N′-bis(1,3,4-thiadiazol-2-yl)-2,6-pyridinedicarboxamide (2) DMSO solvate (2·DMSO) was described.… read more here.
Keywords: complexation properties; diamides synthesis; based diamides; synthesis complexation ... See more keywords
Elemental iodine mediated synthesis of thiadiazole-based dithiafulvalene donors via C(sp2)–S formation
Sign Up to like & getrecommendations! Published in 2019 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2018.11.072
Abstract: Abstract A series of thiadiazole-based dithiafulvalene (DTF) derivatives has been synthesized in moderate yields via iodine-mediated oxidative vinylic C(sp2)–H sulfenylation with mercapto-thiadiazoles. The formation of C(sp2)–S bond was confirmed and characterized by NMR and single… read more here.
Keywords: iodine mediated; based dithiafulvalene; elemental iodine; thiadiazole based ... See more keywords
Regioregular Bis-Pyridal[2,1,3]thiadiazole-Based Semiconducting Polymer for High-Performance Ambipolar Transistors.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.7b10256
Abstract: We report a regioregular bis-pyridal[2,1,3]-thiadiazole (BPT) acceptor strategy to construct the first ambipolar pyridal[2,1,3]thiadiazole-based semiconducting polymer (PBPTV). The use of BPT unit enables PBPTV to achieve high electron affinity, low LUMO level, and extended π-conjugation.… read more here.
Keywords: bis pyridal; regioregular bis; thiadiazole based; based semiconducting ... See more keywords
A novel low-bandgap pyridazine thiadiazole-based conjugated polymer with deep molecular orbital levels
Sign Up to like & getrecommendations! Published in 2020 at "Polymer Chemistry"
DOI: 10.1039/c9py01137d
Abstract: A pyridazine thiadiazole acceptor (PzT) has been utilised in the synthesis of a novel low band-gap D–A copolymer PTTPz. It is a much stronger acceptor in comparison to BT and PyT moieties widely incorporated in… read more here.
Keywords: novel low; thiadiazole based; low bandgap; pyridazine thiadiazole ... See more keywords
Novel cocrystals of the potent 1,2,4-thiadiazole-based neuroprotector with carboxylic acids: virtual screening, crystal structures and solubility performance
Sign Up to like & getrecommendations! Published in 2021 at "New Journal of Chemistry"
DOI: 10.1039/d0nj05644h
Abstract: Five new multicomponent solid forms of the biologically active 1,2,4-thiadiazole derivative (TDZH) with dicarboxylic and hydroxybenzoic acids have been discovered by combined virtual/experimental cocrystal screening. The interplay between the intrinsic hierarchy of the donor/acceptor groups… read more here.
Keywords: neuroprotector carboxylic; thiadiazole based; cocrystals potent; based neuroprotector ... See more keywords
Development of New Antimycobacterial Sulfonyl Hydrazones and 4-Methyl-1,2,3-thiadiazole-Based Hydrazone Derivatives
Sign Up to like & getrecommendations! Published in 2022 at "Antibiotics"
DOI: 10.3390/antibiotics11050562
Abstract: Fifteen 4-methyl-1,2,3-thiadiazole-based hydrazone derivatives 3a–d and sulfonyl hydrazones 5a–k were synthesized. They were characterized by 1H-NMR, 13C NMR, and HRMS. Mycobacterium tuberculosis strain H37Rv was used to assess their antimycobacterial activity. All compounds demonstrated significant… read more here.
Keywords: thiadiazole based; based hydrazone; hydrazone derivatives; methyl thiadiazole ... See more keywords
Novel Thiadiazole-Based Molecules as Promising Inhibitors of Black Fungi and Pathogenic Bacteria: In Vitro Antimicrobial Evaluation and Molecular Docking Studies
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27113613
Abstract: Novel 1,3,4-thiadiazole derivatives were synthesized through the reaction of methyl 2-(4-hydroxy-3-methoxybenzylidene) hydrazine-1-carbodithioate and the appropriate hydrazonoyl halides in the presence of a few drops of diisopropylethylamine. The chemical structure of the newly fabricated compounds was… read more here.
Keywords: molecular docking; thiadiazole based; molecules promising; based molecules ... See more keywords
New 5-Aryl-1,3,4-Thiadiazole-Based Anticancer Agents: Design, Synthesis, In Vitro Biological Evaluation and In Vivo Radioactive Tracing Studies
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceuticals"
DOI: 10.3390/ph15121476
Abstract: A new series of 5-(4-chlorophenyl)-1,3,4-thiadiazole-based compounds featuring pyridinium (3), substituted piperazines (4a–g), benzyl piperidine (4i), and aryl aminothiazoles (5a–e) heterocycles were synthesized. Evaluation of the cytotoxicity potential of the new compounds against MCF-7 and HepG2… read more here.
Keywords: thiadiazole based; evaluation; radioactive tracing; new aryl ... See more keywords