Synthesis and study of the α-amylase inhibitory potential of thiadiazole quinoline derivatives.
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DOI: 10.1016/j.bioorg.2017.08.003
Abstract: α-Amylase is a target for type-2 diabetes mellitus treatment. However, small molecule inhibitors of α-amylase are currently scarce. In the course of developing small molecule α-amylase inhibitors, we designed and synthesized thiadiazole quinoline analogs (1-30),… read more here.
Keywords: thiadiazole quinoline; amylase inhibitory; inhibitory potential; amylase ... See more keywords