Synthesis, in vitro urease inhibition and molecular docking studies of some novel quinazolin-4(3H)-one derivatives containing triazole, thiadiazole and thiosemicarbazide functionalities.
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DOI: 10.1016/j.bioorg.2018.10.031
Abstract: A new series of quinazolinone derivatives containing triazole, thiadiazole, thiosemicarbazide functionalities was synthesized and then screened for their in vitro urease inhibition properties. Most of the compounds showed excellent activity with IC50 values ranging between… read more here.
Keywords: thiosemicarbazide functionalities; vitro urease; thiadiazole thiosemicarbazide; containing triazole ... See more keywords