Retrospective analysis of thiamine deficiency in allogeneic stem cell transplant patients
Sign Up to like & getrecommendations! Published in 2018 at "Annals of Hematology"
DOI: 10.1007/s00277-018-3531-2
Abstract: Dear Editor, Thiamine deficiency is an under-recognized complication of allogeneic stem cell transplantation (allo-SCT). Thiamine plays a key role in cerebral energy utilization. Severe deficiency causes neuronal injury, sometimes leading to Wernicke’s Encephalopathy (WE) [1–4].… read more here.
Keywords: thiamine; deficiency; stem cell; thiamine deficiency ... See more keywords
Riboflavin and thiamine content in extracts of wild-grown plants for medicinal and cosmetic use
Sign Up to like & getrecommendations! Published in 2019 at "Chemical Papers"
DOI: 10.1007/s11696-019-01017-z
Abstract: Products derived from wild-grown plants represent a growing segment of the modern pharmaceutical industry. In recent years, particular attention has been paid to their application in the cosmetic industry. The content of B group vitamins… read more here.
Keywords: wild grown; grown plants; content; riboflavin thiamine ... See more keywords
Impairment of Thiamine Transport at the GUT-BBB-AXIS Contributes to Wernicke’s Encephalopathy
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Neurobiology"
DOI: 10.1007/s12035-017-0811-0
Abstract: Wernicke’s encephalopathy, a common neurological disease, is caused by thiamine (vitamin B1) deficiency. Neuropathy resulting from thiamine deficiency is a hallmark of Wernicke-Korsakoff syndrome in chronic alcohol users. The underlying mechanisms of this deficiency and… read more here.
Keywords: thiamine transport; gut; axis; thiamine ... See more keywords
Effects of Chronic Voluntary Alcohol Drinking on Thiamine Concentrations, Endoplasmic Reticulum Stress, and Oxidative Stress in the Brain of Crossed High Alcohol Preferring Mice
Sign Up to like & getrecommendations! Published in 2019 at "Neurotoxicity Research"
DOI: 10.1007/s12640-019-00032-y
Abstract: Chronic alcohol drinking can damage the central nervous system via many mechanisms. One of these may involve a deficiency of an essential nutrient, thiamine, as a result of chronic alcohol exposure. Although thiamine deficiency (TD)… read more here.
Keywords: stress; mice; thiamine; brain ... See more keywords
PET imaging of 11C-labeled thiamine tetrahydrofurfuryl disulfide, vitamin B1 derivative: First-in-human study.
Sign Up to like & getrecommendations! Published in 2021 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2021.03.119
Abstract: Vitamine B1 thiamine is an essential component for glucose metabolism and energy production. The disulfide derivative, thiamine tetrahydrofurfuryl disulfide (TTFD), is more absorbent compared to readily-available water-soluble thiamine salts since it does not require the… read more here.
Keywords: pet imaging; study; ttfd; 11c ttfd ... See more keywords
[Wernicke encephalopathy: Guiding thiamine prescription].
Sign Up to like & getrecommendations! Published in 2017 at "L'Encephale"
DOI: 10.1016/j.encep.2016.04.011
Abstract: BACKGROUND AND AIM Wernicke's encephalopathy (WE) is a medical emergency. The objective of this paper is to systematically review the literature published over the past 15 years pertaining to prophylactic and curative treatment of WE with… read more here.
Keywords: risk; literature; guiding thiamine; treatment ... See more keywords
Using clinical decision support through the electronic medical record to increase prescribing of high-dose parenteral thiamine in hospitalized patients with alcohol use disorder.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of substance abuse treatment"
DOI: 10.1016/j.jsat.2019.01.017
Abstract: BACKGROUND Patients with alcohol use disorder (AUD) are at an increased risk of developing Wernicke's encephalopathy (WE), a devastating and difficult diagnosis caused by thiamine deficiency. Even as AUD is present in up to 25%… read more here.
Keywords: patients alcohol; increase; group; thiamine ... See more keywords
[Thiamine (vitamin B1) treatment in patients with alcohol dependence].
Sign Up to like & getrecommendations! Published in 2017 at "Presse medicale"
DOI: 10.1016/j.lpm.2016.07.025
Abstract: Thiamine deficiency (vitamin B1) is common in patients with alcohol dependence. Cognitive impairments may be an early consequence of thiamine deficiency. Wernicke's encephalopathy is underdiagnosed and undertreated. In patients with established Wernicke's encephalopathy, parenteral thiamine… read more here.
Keywords: alcohol dependence; thiamine; oral thiamine; day ... See more keywords
Treatment of rats with the JAK-2 inhibitor fedratinib does not lead to experimental Wernicke’s encephalopathy
Sign Up to like & getrecommendations! Published in 2017 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2017.01.041
Abstract: Recent clinical trials suggest that patients with myelofibrosis can develop Wernicke's encephalopathy (WE) when treated with fedratinib, a specific Janus kinase-2 (JAK-2) inhibitor. To investigate this issue, we have examined (1) if fedratinib can produce… read more here.
Keywords: inhibitor; jak inhibitor; treatment; fedratinib lead ... See more keywords
Thiamine (vitamin B1) as an insect repellent: a scoping review
Sign Up to like & getrecommendations! Published in 2022 at "Bulletin of Entomological Research"
DOI: 10.1017/s0007485321001176
Abstract: Abstract While the desire for systemic repellents is high, ineffective repellents put one at risk of insect-vectored pathogens. Vitamin B1, or thiamine, has been touted as a systemic insect repellent since 1943, and denounced as… read more here.
Keywords: thiamine; scoping review; evidence; insect repellent ... See more keywords
De novo synthesis of thiamine (vitamin B1) is the ancestral state in Plasmodium parasites – evidence from avian haemosporidians
Sign Up to like & getrecommendations! Published in 2017 at "Parasitology"
DOI: 10.1017/s0031182017002219
Abstract: Abstract Parasites often have reduced genomes as their own genes become redundant when utilizing their host as a source of metabolites, thus losing their own de novo production of metabolites. Primate malaria parasites can synthesize… read more here.
Keywords: plasmodium parasites; novo synthesis; synthesis thiamine; thiamine ... See more keywords