Articles with "thiazin one" as a keyword



Solid‐Phase Synthesis of 1,3,5,6‐Tetra‐Substituted 3,5‐Dihydroimidazo[4,5‐c][1,2]Thiazin‐4(1H)‐One 2,2‐Dioxide Derivatives

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Published in 2025 at "Journal of Heterocyclic Chemistry"

DOI: 10.1002/jhet.70045

Abstract: The synthesis of 1,3,5,6‐tetra‐substituted 3,5‐dihydroimidazo[4,5‐c][1,2]thiazin‐4(1H)‐one 2,2‐dioxide derivatives was optimized through solid‐phase synthesis. Synthetic strategies such as Merrifield resin, Thorpe‐Ziegler reaction, Mitsunobu reaction, intramolecular cyclization, and desulfonative nucleophilic substitution were employed to synthesize a total of… read more here.

Keywords: dihydroimidazo thiazin; tetra substituted; synthesis; thiazin one ... See more keywords

Synthesis of tetracyclic azasugars fused benzo[e][1,3]thiazin-4-one by the tandem Staudinger/aza-Wittig/cyclization and their HIV-RT inhibitory activity.

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Published in 2018 at "Carbohydrate research"

DOI: 10.1016/j.carres.2017.12.005

Abstract: Azasugar aldehydes 6a and 6b containing azido groups were prepared from D-mannose. Three novel tetracyclic azasugars fused benzo[e][1,3]thiazin-4-one 9a-1, 9a-2 and 9a-3 were conveniently synthesized from 6a by the tandem intramolecular Staudinger/aza-Wittig/cyclization reaction under microwave… read more here.

Keywords: tetracyclic azasugars; fused benzo; benzo thiazin; azasugars fused ... See more keywords

Investigating Solvent-Induced Changes in Structure and Nonlinear Optical Behavior of Thiazine Derivatives

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Published in 2024 at "Journal of the Brazilian Chemical Society"

DOI: 10.21577/0103-5053.20240014

Abstract: In this study, we examine the effects of solvent media on the structural and optical behaviors of two isomers of thiazine derivatives: rac-2-(4-nitrophenyl)-3-phenyl-2,3,5,6-tetrahydro4H-1,3-thiazin-4-one and (2S)-2-(3-nitrophenyl)-3-phenyl-2,3,5,6-tetrahydro-4H-1,3-thiazin4-one. The solvent effects were modeled using the polarizable continuum model… read more here.

Keywords: nonlinear optical; thiazine derivatives; phenyl tetrahydro; nitrophenyl phenyl ... See more keywords