Articles with "thiazole dihydrofuran" as a keyword



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Design, synthesis, in vitro and in silico studies of some novel thiazole-dihydrofuran derivatives as aromatase inhibitors.

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Published in 2021 at "Bioorganic chemistry"

DOI: 10.1016/j.bioorg.2021.105123

Abstract: Aromatase inhibitors used against hormone-dependent breast cancer, especially in post-menopausal women, are very susceptible to the development of resistance due to their limited number and long-term use. In this study, it is aimed to obtain… read more here.

Keywords: thiazole dihydrofuran; aromatase inhibitors; vitro; cell ... See more keywords