Synthesis of a Thiazole Library via an Iridium-Catalyzed Sulfur Ylide Insertion Reaction
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DOI: 10.1021/acs.orglett.2c02996
Abstract: A library of thiazoles and selenothiazoles were synthesized via Ir-catalyzed ylide insertion chemistry. This process is a functional group, particularly heterocycle-substituent tolerant. This was applied to the synthesis of fanetizole, an anti-inflammatory drug, and a… read more here.
Keywords: ylide insertion; synthesis thiazole; thiazole library; insertion ... See more keywords