Directed Evolution of Aerotolerance in Sulfide-Dependent Thiazole Synthases
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DOI: 10.1021/acssynbio.2c00512
Abstract: Sulfide-dependent THI4 thiazole synthases could potentially be used to replace plant cysteine-dependent suicide THI4s, whose high protein turnover rates make thiamin synthesis exceptionally energy-expensive. However, sulfide-dependent THI4s are anaerobic or microoxic enzymes and hence unadapted… read more here.
Keywords: sulfide dependent; thi4s; thiazole synthases; directed evolution ... See more keywords