ZnO‐Nanorods as an Efficient Catalyst for the Synthesis of 1,3‐Thiazolidine Derivatives by Aqueous Multicomponent Reactions of Isothiocyanates
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DOI: 10.1002/jhet.2789
Abstract: A simple three-components reaction between alkynes, primary amines, and isothiocyanates in the presence of nanophase ZnO catalysts in aqueous medium at room temperature is reported which produced 1,3-thiazolidine derivatives in good yields. Particularly valuable features… read more here.
Keywords: catalyst synthesis; efficient catalyst; zno nanorods; thiazolidine derivatives ... See more keywords
Tetra-substituted phthalocyanines bearing thiazolidine derivatives: synthesis, anticancer activity on different cancer cell lines, and molecular docking studies.
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DOI: 10.1039/d1dt02023d
Abstract: In the first step, (4R)-2-(2-hydroxyphenyl)thiazolidine-4-carboxylic acid (c) and 2-(2-(3,4-dicyanophenoxy)phenyl)thiazolidine-4-carboxylic acid (1) were prepared. Then, the peripherally tetra-substituted metallophthalocyanines [ZnPc (2), CuPc (3), and CoPc (4)] were synthesized by using 1. The structures of the obtained… read more here.
Keywords: tetra substituted; cell lines; anticancer activity; molecular docking ... See more keywords
Design and synthesis of thiazolidine-2,4-diones hybrids with 1,2-dihydroquinolones and 2-oxindoles as potential VEGFR-2 inhibitors: in-vitro anticancer evaluation and in-silico studies
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DOI: 10.1080/14756366.2022.2085693
Abstract: Abstract A thiazolidine-2,4-dione nucleus was molecularly hybridised with the effective antitumor moieties; 2-oxo-1,2-dihydroquinoline and 2-oxoindoline to obtain new hybrids with potential activity against VEGFR-2. The cytotoxic effects of the synthesised derivatives against Caco-2, HepG-2, and… read more here.
Keywords: design synthesis; vegfr; synthesis thiazolidine; thiazolidine ... See more keywords
Design, Synthesis, Hypoglycemic Activity and Molecular Docking Studies of 3-substituted-5- [(furan-2-yl)-methylene]-thiazolidine-2,4-dione Derivatives
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DOI: 10.5530/ijper.55.1.30
Abstract: Background: From the wide range of previous literature studies indicated that thiazolidinedione’s reacts with substituted benzaldehydes undergoes knoevenagel condensation gives respective arylidene derivatives. In our attempt all the titled compounds were designed and developed by… read more here.
Keywords: thiazolidine dione; molecular docking; furan methylene; activity ... See more keywords