2-Mercaptomethyl-thiazolidines use conserved aromatic–S interactions to achieve broad-range inhibition of metallo-β-lactamases†
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DOI: 10.1039/d0sc05172a
Abstract: Infections caused by multidrug resistant (MDR) bacteria are a major public health threat. Carbapenems are among the most potent antimicrobial agents that are commercially available to treat MDR bacteria. Bacterial production of carbapenem-hydrolysing metallo-β-lactamases (MBLs)… read more here.
Keywords: mercaptomethyl thiazolidines; thiazolidines use; use conserved; conserved aromatic ... See more keywords