Enantioselective acyl-trifluoromethylation of olefins by bulky thiazolium carbene catalysis
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DOI: 10.1038/s41467-025-58423-z
Abstract: Enantioenriched α-chiral β-fluorinated ketones are valuable structural motifs with application in several fields. The recently emerged concept of NHC-catalyzed radical acyl-trifluoromethylation of olefins offers a rapid route to construct racemic β-fluorinated ketones in a single… read more here.
Keywords: trifluoromethylation olefins; acyl trifluoromethylation; thiazolium; fluorinated ketones ... See more keywords
A Purification-Free Method for the Synthesis of Thiazolium Salts Using P2S5-Py2 Complex or P4S10
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DOI: 10.1139/cjc-2024-0101
Abstract: An expedient method to prepare thiazolium salts using the P2S5-Py2 complex or P4S10 has been studied. A variety of thiazolium salts can be rapidly accessed by the clean reaction between readily available α-formamido ketones and… read more here.
Keywords: method; salts using; thiazolium; p2s5 py2 ... See more keywords
Antibacterial Polymers Based on Poly(2-hydroxyethyl methacrylate) and Thiazolium Groups with Hydrolytically Labile Linkages Leading to Inactive and Low Cytotoxic Compounds
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DOI: 10.3390/ma14237477
Abstract: Herein, we develop a well-defined antibacterial polymer based on poly(2-hydroxyethyl methacrylate) (PHEMA) and a derivative of vitamin B1, easily degradable into inactive and biocompatible compounds. Hence, thiazole moiety was attached to HEMA monomer through a… read more here.
Keywords: thiazolium; polymer; degradation; hydroxyethyl methacrylate ... See more keywords