Articles with "thiazolo" as a keyword



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Synthesis, characterization, and DFT modeling of novel organic compound thin films derived from 2-amino-4-(2-hydroxy-3-methoxyphenyl)-4H-thiazolo[3,2-a][1,3,5]triazin-6(7H)-one

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Published in 2020 at "Optical Materials"

DOI: 10.1016/j.optmat.2020.109915

Abstract: Abstract A smooth and effective protocol was proven to produce 2-amino-4-(2-hydroxy-3-methoxy-phenyl)-6-oxo-4H-thiazolo[3,2-a][1,3,5]triazine [2aTZ] via one-pot ternary condensation of easily available mercaptoacetic acid, o-vanillin and dicyandiamide along with ammonium acetate (CH3COONH4) as a catalyst. The chemical structure… read more here.

Keywords: dft; compound thin; amino hydroxy; thiazolo ... See more keywords

Visible-light driven regioselective synthesis, characterization and binding studies of 2-aroyl-3-methyl-6,7-dihydro-5H-thiazolo[3,2-a]pyrimidines with DNA and BSA using biophysical and computational techniques

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Published in 2021 at "Scientific Reports"

DOI: 10.1038/s41598-021-01037-4

Abstract: In recent times, fused azaheterocycles emerged as impressive therapeutic agents. Binding studies of such azaheterocycles with biomolecules is an important subject for pharmaceutical and biochemical studies aiming at the design and development of new drugs.… read more here.

Keywords: aroyl methyl; methyl dihydro; binding studies; thiazolo pyrimidines ... See more keywords
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Regioselective convergent synthesis of 2-arylidene thiazolo[3,2-a]pyrimidines as potential anti-chikungunya agents

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Published in 2020 at "RSC Advances"

DOI: 10.1039/d0ra00257g

Abstract: Convergent and convenient regioselective synthesis of novel thiazolo[2,3-a]pyrimidine derivatives was accomplished using the one-pot reaction of 6-ethylthiouracil, bromoacetic acid, anhydrous sodium acetate, acetic anhydride, acetic acid and suitable aldehyde. X-ray crystallographic study reveals the presence… read more here.

Keywords: arylidene thiazolo; regioselective convergent; synthesis arylidene; thiazolo ... See more keywords
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Rapid synthesis of (E)-5-amino-N′-benzylidene-8-nitro-7-aryl-3,7-dihydro-2H-thiazolo[3,2-a]pyridine-6-carbohydrazide derivatives

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Published in 2018 at "Journal of Sulfur Chemistry"

DOI: 10.1080/17415993.2017.1422504

Abstract: ABSTRACT A variety of novel thiazolo/oxazolo pyridine derivatives were synthesized via an efficient, one-pot, multi-component reaction of enamines derived from the addition of cysteamine hydrochloride/ethanolamine to 1,1-bis(methylthio)-2-nitroethene with aromatic aldehydes and cyanoacetohydrazide in the presence… read more here.

Keywords: benzylidene nitro; rapid synthesis; amino benzylidene; pyridine ... See more keywords