Simple Synthesis of Fused Thiazolo[4,5-b]pyridines through Successive SNAr Processes
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DOI: 10.1055/s-0040-1705960
Abstract: A convenient process is described for the synthesis of novel thiazolo[4,5-b]pyridines fused with triazole or pyrimidine rings. The base-promoted reactions of 2-chloro-3-nitropyridines with 1,3-(S,N)-binucleophiles (triazole-5-thiols, 4-oxopyrimidine-2-thiones) resulted in nucleophilic substitution of the chlorine atom and… read more here.
Keywords: thiazolo pyridines; fused thiazolo; pyridines successive; simple synthesis ... See more keywords