Three-Component One-Pot Construction of 2-Aryl-4H-benzo[4,5]thiazolo[3,2-a]pyrimidines Using Solid Calcium Carbide as a Surrogate of Gaseous Acetylene.
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DOI: 10.1021/acs.orglett.2c02331
Abstract: A concise method for the construction of 2-aryl-4H-benzo[4,5]thiazolo[3,2-a]pyrimidines using solid calcium carbide instead of gaseous acetylene as an alkyne source and 2-aminobenzothiazoles and aromatic aldehydes as substrates through one-pot three-component cascade reactions is described. The… read more here.
Keywords: using solid; aryl benzo; benzo thiazolo; pyrimidines using ... See more keywords
Visible-light driven regioselective synthesis, characterization and binding studies of 2-aroyl-3-methyl-6,7-dihydro-5H-thiazolo[3,2-a]pyrimidines with DNA and BSA using biophysical and computational techniques
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DOI: 10.1038/s41598-021-01037-4
Abstract: In recent times, fused azaheterocycles emerged as impressive therapeutic agents. Binding studies of such azaheterocycles with biomolecules is an important subject for pharmaceutical and biochemical studies aiming at the design and development of new drugs.… read more here.
Keywords: aroyl methyl; methyl dihydro; binding studies; thiazolo pyrimidines ... See more keywords