A facile synthesis of some novel thiazoles, arylazothiazoles, and pyrazole linked to thiazolyl coumarin as antibacterial agents
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DOI: 10.1080/00397911.2020.1782431
Abstract: Abstract 5-bromosalicylaldehyde (1) was reacted with thiosemicarbazide to afford thiosemicarbazone derivative 2. The latter underwent cyclocondensation upon reaction with α-haloester, α-haloketone as well as hydrazonoyl halides affording 1,3-thiazoles and arylazothiazoles 3-6, respectively. On the other… read more here.
Keywords: strong active; active toward; thiazolyl coumarin; facile synthesis ... See more keywords
Computational and biological studies of novel thiazolyl coumarin derivatives synthesized through Suzuki coupling
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DOI: 10.3906/kim-2005-19
Abstract: The current investigation presents the synthesis, computational molecular-docking and biological activity studies of arylated thiazole coumarins. Aryl substituted thiazolyl coumarin derivatives were synthesized via Suzuki cross-coupling reaction. A detailed reaction condition optimization revealed that the… read more here.
Keywords: thiazolyl coumarin; coumarin; derivatives synthesized; biological studies ... See more keywords