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Published in 2019 at "Canadian Journal of Chemistry"
DOI: 10.1139/cjc-2018-0220
Abstract: This work presents the preparation of a new series of N-(substituted phenyl)-2-(4-oxo-5-(4-(thieno[2,3-d]-pyrimidin-4-yloxy)benzylidene)-2-thioxothiazolidin-3-yl)acetamide derivatives (8a–8l). A condensation reaction of thienopyrimidin-2-thioxothiazolidin-4-one derivative (5) with various 2-chloro-N-phenylacetamides (7a–7l) was employed to afford the new thienopyrimidine tagged rhodanine derivatives…
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Keywords:
thienopyrimidine;
antimicrobial activity;
activity novel;
synthesis antimicrobial ... See more keywords
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Published in 2019 at "Journal of microbiology and biotechnology"
DOI: 10.4014/jmb.1811.11046
Abstract: A series of thienopyrimidine compounds (6Aa-g and 6Ba-d) were synthesized and characterized by NMR spectroscopy and mass spectrometry. These compounds (6Aa-g and 6Ba-d) potently inhibited STAT3 expression induced by IL-6 in a dose-dependent manner with…
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Keywords:
thienopyrimidine;
synthesis thienopyrimidine;
derivatives inhibitors;
inhibitors stat3 ... See more keywords