Into Thin Air: Hypoxia Drives Metabolic and Epigenomic Deregulation of Lethal Pediatric Ependymoma.
Sign Up to like & getrecommendations! Published in 2020 at "Developmental cell"
DOI: 10.1016/j.devcel.2020.06.020
Abstract: Posterior fossa type A (PFA) ependymoma is a lethal pediatric brain tumor proposed to be driven solely by epigenetic deregulation. Michealraj et al. (2020) demonstrate that hypoxia reprograms PFA metabolism and, subsequently, the epigenome toward H3K27… read more here.
Keywords: air hypoxia; lethal pediatric; ependymoma; deregulation ... See more keywords
Travel on thin air
Sign Up to like & getrecommendations! Published in 2019 at "Nature Geoscience"
DOI: 10.1038/s41561-019-0346-2
Abstract: Pyroclastic density currents generate a basal air cushion that reduces friction with the ground, reveal laboratory experiments. This explains their ability to travel rapidly over large distances from their volcanic source. read more here.
Keywords: air; thin air; travel thin; travel ... See more keywords
Out of Thin Air? Astrobiology and Atmospheric Chemotrophy
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DOI: 10.1089/ast.2021.0066
Abstract: The emerging understanding of microbial trace gas chemotrophy as a metabolic strategy to support energy and carbon acquisition for microbial survival and growth has significant implications in the search for past, and even extant, life… read more here.
Keywords: astrobiology; air astrobiology; astrobiology atmospheric; chemotrophy ... See more keywords
Thin Air, Thick Vessels: Historical and Current Perspectives on Hypoxic Pulmonary Hypertension
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2019.00093
Abstract: The association between pulmonary hypertension (PH) and hypoxia is well-established, with two key mechanistic processes, hypoxic pulmonary vasoconstriction and hypoxia-induced vascular remodeling, driving changes in pulmonary arterial pressure. In contrast to other forms of pulmonary… read more here.
Keywords: pulmonary hypertension; vascular remodeling; hypoxic pulmonary; hypertension ... See more keywords