Synthesis and antibacterial study of cell-penetrating peptide conjugated trifluoroacetyl and thioacetyl lysine modified peptides.
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DOI: 10.1016/j.ejmech.2021.113447
Abstract: Substrate-based sirtuin inhibitors target bacterial genome and RNA and provide a promising approach to address bacterial resistance issues, if cellular internalisation can be achieved. We designed N-trifluoroacetyl lysine and N-thioacetyl lysine peptides (KP 13, KP… read more here.
Keywords: thioacetyl lysine; lysine; penetrating peptide; study ... See more keywords