Thioamide‐Bridged Nucleic Acid (thioAmNA) Containing Thymine or 2‐Thiothymine: Duplex‐Forming Ability, Base Discrimination, and Enzymatic Stability
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DOI: 10.1002/cbic.201800702
Abstract: Oligonucleotides containing bridged nucleic acids (BNAs) show high duplex‐forming ability towards target single‐stranded RNA, so many BNAs have been developed for antisense applications. Amide‐bridged nucleic acids (AmNAs), which are BNA analogues bearing an amide bond… read more here.
Keywords: duplex forming; forming ability; thioamna; bridged nucleic ... See more keywords