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Published in 2018 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2018.09.004
Abstract: A number of naturally occurring compounds such as paclitaxel, vinblastine, combretastatin, and colchicine exert their therapeutic effect by changing the dynamics of tubulin and its polymer form, microtubules. The identification of tubulin as a potential…
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Keywords:
thiocolchicine;
molecular docking;
antiproliferative activity;
synthesis antiproliferative ... See more keywords