Synthesis and Evaluation of Small Molecule Drug Conjugates Harnessing Thioester-Linked Maytansinoids
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DOI: 10.3390/pharmaceutics14071316
Abstract: Ligand-targeting drug conjugates are a class of clinically validated biopharmaceutical drugs constructed by conjugating cytotoxic drugs with specific disease antigen targeting ligands through appropriate linkers. The integrated linker-drug motif embedded within such a system can… read more here.
Keywords: small molecule; thioester linked; drug conjugates; molecule drug ... See more keywords