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Published in 2025 at "ChemPlusChem"
DOI: 10.1002/cplu.202500513
Abstract: Benzothiazoles, including the cationic thioflavin T and its variants, are of immense interest because of their therapeutic potential and applications as biomolecular fluorescence probes. This study investigates the photophysics of an interesting benzothiazole derivative, TEG-BTA-2,…
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Keywords:
teg bta;
photophysics contrasting;
fluorescence;
thioflavin ... See more keywords
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Published in 2023 at "Nanoscale"
DOI: 10.1039/d2nr06389a
Abstract: The development of effective methods for the detection of protein misfolding is highly beneficial for early stage medical diagnosis and the prevention of many neurodegenerative diseases. Self-assembled plasmonic nanoantennas with precisely tunable nanogaps show extraordinary…
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Keywords:
thioflavin;
detection;
dna origami;
marker ... See more keywords
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Published in 2020 at "Science Advances"
DOI: 10.1126/sciadv.abc1449
Abstract: Single-molecule imaging reveals the oligomerization state specificity of drug on its protein receptor. Selective oligomerization is a common phenomenon existing widely in the formation of intricate biological structures in nature. The precise design of drug…
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Keywords:
recognition human;
selective oligomerization;
oligomerization state;
thioflavin ... See more keywords
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Published in 2023 at "Journal of Chemical Research"
DOI: 10.1177/17475198221139085
Abstract: A label- and enzyme-free fluorescence assay based on thioflavin T–induced G-quadruplexes is developed to sensitively and specifically detect telomerase activity. Thioflavin T has a dual role as an efficient inducer and fluorescent probe, and the…
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Keywords:
thioflavin;
fluorescence;
assay;
telomerase activity ... See more keywords
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Published in 2022 at "Molecules"
DOI: 10.3390/molecules27186093
Abstract: A novel, label-free fluorescent assay has been developed for the detection of trypsin by using thioflavin T as a fluorescent probe. A specific DNA aptamer can be combined by adding cytochrome c. Trypsin hydrolyzes the…
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Keywords:
trypsin;
label free;
detection;
detection trypsin ... See more keywords