Selective recognition of the amyloid marker single thioflavin T using DNA origami-based gold nanobipyramid nanoantennas.
Sign Up to like & getrecommendations! Published in 2023 at "Nanoscale"
DOI: 10.1039/d2nr06389a
Abstract: The development of effective methods for the detection of protein misfolding is highly beneficial for early stage medical diagnosis and the prevention of many neurodegenerative diseases. Self-assembled plasmonic nanoantennas with precisely tunable nanogaps show extraordinary… read more here.
Keywords: thioflavin; detection; dna origami; marker ... See more keywords
Molecular recognition of human islet amyloid polypeptide assembly by selective oligomerization of thioflavin T
Sign Up to like & getrecommendations! Published in 2020 at "Science Advances"
DOI: 10.1126/sciadv.abc1449
Abstract: Single-molecule imaging reveals the oligomerization state specificity of drug on its protein receptor. Selective oligomerization is a common phenomenon existing widely in the formation of intricate biological structures in nature. The precise design of drug… read more here.
Keywords: recognition human; selective oligomerization; oligomerization state; thioflavin ... See more keywords
A label- and enzyme-free fluorescence assay based on thioflavin T–induced G-quadruplexes for the detection of telomerase activity
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Chemical Research"
DOI: 10.1177/17475198221139085
Abstract: A label- and enzyme-free fluorescence assay based on thioflavin T–induced G-quadruplexes is developed to sensitively and specifically detect telomerase activity. Thioflavin T has a dual role as an efficient inducer and fluorescent probe, and the… read more here.
Keywords: thioflavin; fluorescence; assay; telomerase activity ... See more keywords
A Label-Free Fluorescence Aptasensor Based on G-Quadruplex/Thioflavin T Complex for the Detection of Trypsin
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27186093
Abstract: A novel, label-free fluorescent assay has been developed for the detection of trypsin by using thioflavin T as a fluorescent probe. A specific DNA aptamer can be combined by adding cytochrome c. Trypsin hydrolyzes the… read more here.
Keywords: trypsin; label free; detection; detection trypsin ... See more keywords