Thiol‐based copper handling by the copper chaperone Atox1
Sign Up to like & getrecommendations! Published in 2017 at "IUBMB Life"
DOI: 10.1002/iub.1620
Abstract: Human antioxidant protein 1 (Atox1) plays a crucial role in cellular copper homeostasis. Atox1 captures cytosolic copper for subsequent transfer to copper pumps in trans Golgi network, thereby facilitating copper supply to various copper‐dependent oxidereductases… read more here.
Keywords: atox1; based copper; copper handling; thiol based ... See more keywords
Ruthenium Nanoparticles Immobilized on Nano-silica Functionalized with Thiol-Based Dendrimer: A Nanocomposite Material for Oxidation of Alcohols and Epoxidation of Alkenes
Sign Up to like & getrecommendations! Published in 2018 at "Catalysis Letters"
DOI: 10.1007/s10562-018-2313-8
Abstract: In this work, ruthenium nanoparticles were immobilized on thiol-based dendrimer functionalized nano-silica and its catalytic activity was investigated in the oxidation reactions. To do this, silica nanoparticles were functionalized with a thiol-based dendrimer, and this… read more here.
Keywords: oxidation; ruthenium nanoparticles; nanoparticles immobilized; thiol based ... See more keywords
Thiol-based michael-type addition. A systematic evaluation of its controlling factors
Sign Up to like & getrecommendations! Published in 2020 at "Tetrahedron"
DOI: 10.1016/j.tet.2020.131637
Abstract: Abstract This paper is about the factors controlling kinetics and product stability of this popular bioconjugation reaction. We demonstrate that a) thiol pKa, i.e. the amount of thiolates, is the only determinant of the reaction… read more here.
Keywords: type addition; addition systematic; michael type; reaction ... See more keywords
Catalysis of Peroxide Reduction by Fast Reacting Protein Thiols.
Sign Up to like & getrecommendations! Published in 2019 at "Chemical reviews"
DOI: 10.1021/acs.chemrev.9b00371
Abstract: Life on Earth evolved in the presence of hydrogen peroxide, and other peroxides also emerged before and with the rise of aerobic metabolism. They were considered only as toxic byproducts for many years. Nowadays, peroxides… read more here.
Keywords: reduction; catalysis peroxide; peroxide reduction; fast reacting ... See more keywords
Thiol-based chemical probes exhibit antiviral activity against SARS-CoV-2 via allosteric disulfide disruption in the spike glycoprotein
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2120419119
Abstract: Significance Some coronaviruses utilize angiotensin-converting enzyme 2 (ACE2) for entry into host cells. Although reducing agents, such as N-acetylcysteine, disrupt viral binding to ACE2 in general, these compounds are cytotoxic, have low potency, and because… read more here.
Keywords: based chemical; sars cov; thiol; thiol based ... See more keywords
Thiol‐based redox sensing in the methyltransferase associated sensor kinase RdmS in Methanosarcina acetivorans
Sign Up to like & getrecommendations! Published in 2019 at "Environmental Microbiology"
DOI: 10.1111/1462-2920.14541
Abstract: Organisms have evolved signal transduction systems to quickly adapt their lifestyle to internal and environmental changes. While protein kinases and two-component systems are widely distributed in Bacteria, they are also found in Archaea but are… read more here.
Keywords: kinase rdms; methanosarcina acetivorans; based redox; kinase ... See more keywords
TrmB Family Transcription Factor as a Thiol-Based Regulator of Oxidative Stress Response
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DOI: 10.1128/mbio.00633-22
Abstract: TrmB-like proteins, while not yet associated with redox stress, are found in bacteria and widespread in archaea. Here, we expand annotation of a large group of TrmB-like single winged-helix DNA binding domain proteins from diverse… read more here.
Keywords: stress; dna; trmb like; oxidative stress ... See more keywords
Towards Initial Indications for a Thiol-Based Redox Control of Arabidopsis 5-Aminolevulinic Acid Dehydratase
Sign Up to like & getrecommendations! Published in 2018 at "Antioxidants"
DOI: 10.3390/antiox7110152
Abstract: Thiol-based redox control is one of the important posttranslational mechanisms of the tetrapyrrole biosynthesis pathway. Many enzymes of the pathway have been shown to interact with thioredoxin (TRX) and Nicotinamide adenine dinucleotide phosphate (NADPH)-dependent thioredoxin… read more here.
Keywords: based redox; aminolevulinic acid; thiol based; acid dehydratase ... See more keywords