Synthesis of Functional Pectin‐Based Hydrogels via Thiol‐Maleimide Click Reaction for Enhanced Drug Encapsulation and Release
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Applied Polymer Science"
DOI: 10.1002/app.56837
Abstract: This work describes the synthesis and characterization of a novel hydrogel system based on pectin (PT) functionalized with thiol and maleimide groups and cross‐linked by thiol‐maleimide click chemistry. Thiolated PT (PT‐SH) and maleimide‐modified PT (PT‐Ma)… read more here.
Keywords: thiol maleimide; maleimide; maleimide click; hydrogel ... See more keywords
Marriage of ring-opening metathesis polymerization and thiol-maleimide chemistries: Direct polymerization of prefunctionalized monomers or postpolymerization modification?
Sign Up to like & getrecommendations! Published in 2017 at "Polymer"
DOI: 10.1016/j.polymer.2017.06.018
Abstract: Abstract Two distinct synthetic methodologies to furnish polynorbornene bearing thiol-maleimide adduct side groups, namely direct ring-opening metathesis polymerization (ROMP) of prefunctionalized monomers and postpolymerization modification, were investigated and compared in this study. ROMP of thiol-maleimide… read more here.
Keywords: polymerization; postpolymerization modification; thiol maleimide;
Fast-Forming Dissolvable Redox-Responsive Hydrogels: Exploiting the Orthogonality of Thiol–Maleimide and Thiol–Disulfide Exchange Chemistry
Sign Up to like & getrecommendations! Published in 2022 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.2c00209
Abstract: Fast-forming yet easily dissolvable hydrogels (HGs) have potential applications in wound healing, burn incidences, and delivery of therapeutic agents. Herein, a combination of a thiol–maleimide conjugation and thiol–disulfide exchange reaction is employed to fabricate fast-forming… read more here.
Keywords: thiol; thiol maleimide; chemistry; fast forming ... See more keywords