Enhancing the Activity of Surface Immobilised Antimicrobial Peptides Using Thiol-Mediated Tethering to Poly(Ethylene Glycol).
Sign Up to like & getrecommendations! Published in 2023 at "Macromolecular bioscience"
DOI: 10.1002/mabi.202200411
Abstract: Considering the need for versatile surface coatings that can display multiple bioactive signals and chemistries, the use of more novel surface modification methods are starting to emerge. Thiol-mediated conjugation of biomolecules has been shown to… read more here.
Keywords: poly ethylene; surface; antimicrobial peptides; ethylene glycol ... See more keywords
Unexpected transformations of 3-(bromoacetyl)coumarin provides new evidence for the mechanism of thiol mediated dehalogenation of α-halocarbonyls
Sign Up to like & getrecommendations! Published in 2017 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2017.01.082
Abstract: Abstract The mechanism for the thiol mediated dehalogenation of α-halogenated carbonyls has remained an unresolved problem, despite its ongoing application in synthetic organic chemistry. Nakamura and co-workers first proposed that net dehalogenation occurs via sequential… read more here.
Keywords: dehalogenation; mechanism; thiol mediated; bromoacetyl coumarin ... See more keywords