Reversible Conjugate Addition in Thiol‐Mediated Uptake
Sign Up to like & getrecommendations! Published in 2025 at "Helvetica Chimica Acta"
DOI: 10.1002/hlca.202500091
Abstract: Dynamic covalent chemistry involving conjugate addition requires reversibility under specific conditions. In classical systems, reversible Michael addition of thiols is achieved using α‐cyano acrylamides. The more recent oxSTEF reagents introduce β,β‐bissulf(ox)ido enones instead to achieve… read more here.
Keywords: thiol mediated; mediated uptake; addition; conjugate addition ... See more keywords
Enhancing the Activity of Surface Immobilised Antimicrobial Peptides Using Thiol-Mediated Tethering to Poly(Ethylene Glycol).
Sign Up to like & getrecommendations! Published in 2023 at "Macromolecular bioscience"
DOI: 10.1002/mabi.202200411
Abstract: Considering the need for versatile surface coatings that can display multiple bioactive signals and chemistries, the use of more novel surface modification methods are starting to emerge. Thiol-mediated conjugation of biomolecules has been shown to… read more here.
Keywords: poly ethylene; surface; antimicrobial peptides; ethylene glycol ... See more keywords
Unexpected transformations of 3-(bromoacetyl)coumarin provides new evidence for the mechanism of thiol mediated dehalogenation of α-halocarbonyls
Sign Up to like & getrecommendations! Published in 2017 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2017.01.082
Abstract: Abstract The mechanism for the thiol mediated dehalogenation of α-halogenated carbonyls has remained an unresolved problem, despite its ongoing application in synthetic organic chemistry. Nakamura and co-workers first proposed that net dehalogenation occurs via sequential… read more here.
Keywords: dehalogenation; mechanism; thiol mediated; bromoacetyl coumarin ... See more keywords