Development of a HPLC-MS/MS method for assessment of thiol redox status in human tear fluids.
Sign Up to like & getrecommendations! Published in 2021 at "Analytical biochemistry"
DOI: 10.1016/j.ab.2021.114295
Abstract: Oxidative stress is reported to be part of the pathology of many ocular diseases. For the diagnosis of ocular diseases, tear fluid has unique advantages. Although numerous analytical methods exist for the measurement of different… read more here.
Keywords: tear fluids; thiol redox; hplc method;
Role of thiol redox regulation in the mitochondrial signaling network
Sign Up to like & getrecommendations! Published in 2018 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2018.04.225
Abstract: Reactive oxygen species (ROS) are not only damaging molecules but are also involved in redox signaling events. In mitochondria, thiol redox state is finely tuned mainly by the thioredoxin and the glutathione systems. Cyclophilin D… read more here.
Keywords: thiol redox; redox; mitochondrial signaling; redox regulation ... See more keywords
Identification of new targets of S-nitrosylation in neural stem cells by thiol redox proteomics
Sign Up to like & getrecommendations! Published in 2020 at "Redox Biology"
DOI: 10.1016/j.redox.2020.101457
Abstract: Nitric oxide (NO) is well established as a regulator of neurogenesis. NO increases the proliferation of neural stem cells (NSC), and is essential for hippocampal injury-induced neurogenesis following an excitotoxic lesion. One of the mechanisms… read more here.
Keywords: redox proteomics; neurogenesis; stem; stem cells ... See more keywords
Stoichiometric Thiol Redox Proteomics for Quantifying Cellular Responses to Perturbations
Sign Up to like & getrecommendations! Published in 2021 at "Antioxidants"
DOI: 10.3390/antiox10030499
Abstract: Post-translational modifications regulate the structure and function of proteins that can result in changes to the activity of different pathways. These include modifications altering the redox state of thiol groups on protein cysteine residues, which… read more here.
Keywords: redox proteomics; redox; stoichiometric thiol; proteomics quantifying ... See more keywords
Oxidants, Antioxidants and Thiol Redox Switches in the Control of Regulated Cell Death Pathways
Sign Up to like & getrecommendations! Published in 2020 at "Antioxidants"
DOI: 10.3390/antiox9040309
Abstract: It is well appreciated that biological reactive oxygen and nitrogen species such as hydrogen peroxide, superoxide and nitric oxide, as well as endogenous antioxidant systems, are important modulators of cell survival and death in diverse… read more here.
Keywords: regulated cell; death; death pathways; cell death ... See more keywords
Immunological Techniques to Assess Protein Thiol Redox State: Opportunities, Challenges and Solutions
Sign Up to like & getrecommendations! Published in 2020 at "Antioxidants"
DOI: 10.3390/antiox9040315
Abstract: To understand oxidative stress, antioxidant defense, and redox signaling in health and disease it is essential to assess protein thiol redox state. Protein thiol redox state is seldom assessed immunologically because of the inability to… read more here.
Keywords: state; protein thiol; assess protein; redox state ... See more keywords