Redox‐responsive microbeads containing thiolated pectin‐doxorubicin conjugate inhibit tumor growth and metastasis: An in vitro and in vivo study
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Pharmaceutics"
DOI: 10.1016/j.ijpharm.2018.04.052
Abstract: ABSTRACT The objective of this study was to investigate the in vitro cytotoxicity and in vivo anticancer efficacy of redox‐responsive microbeads containing thiolated pectin–doxorubicin (DOX) conjugate. Oral microbeads were coated with an enteric polymer to… read more here.
Keywords: containing thiolated; thiolated pectin; study; coated microbeads ... See more keywords
Mucoadhesive Properties of Thiolated Pectin-Based Pellets Prepared by Extrusion-Spheronization Technique.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of pharmaceutical sciences"
DOI: 10.1016/j.xphs.2017.01.028
Abstract: The aim of this study was to develop mucoadhesive pellets on a thiolated pectin base using the extrusion-spheronization technique. Thiolation of pectin was performed by esterification with thioglycolic acid. The molecular weight and thiol group… read more here.
Keywords: thiolated pectin; spheronization technique; pectin; extrusion spheronization ... See more keywords