The oxidation state of cysteine thiols on the ectodomain of TLR2 and TLR4 influences intracellular signaling.
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DOI: 10.1016/j.imbio.2019.12.004
Abstract: Signal transduction by the Toll-like receptors (TLRs) is a key component of innate immunity against many pathogens and also underlies a large burden of human diseases. Therefore, the mechanisms and regulation of signaling from the… read more here.
Keywords: oxidation; cysteine; intracellular signaling; tlr2 tlr4 ... See more keywords