Thiophene‐containing compounds with antimicrobial activity
Sign Up to like & getrecommendations! Published in 2022 at "Archiv der Pharmazie"
DOI: 10.1002/ardp.202100462
Abstract: Thiophene, as a member of the group of five‐membered heterocycles containing one heteroatom, is one of the simplest heterocyclic systems. Many synthetic strategies allow the accurate positioning of various functionalities onto the thiophene ring. This… read more here.
Keywords: compounds antimicrobial; antimicrobial activity; thiophene; thiophene containing ... See more keywords
Silver(I) pyridinyl complexes with benzothiazole, thiophene, and furan moieties: DNA/protein‐binding, antibacterial, antioxidant, and anticancer studies
Sign Up to like & getrecommendations! Published in 2022 at "Archiv der Pharmazie"
DOI: 10.1002/ardp.202200308
Abstract: We have synthesized and characterized nine Ag(I) complexes of Schiff bases containing thiophene, furan, and pyridine moieties for in vitro antibacterial, antioxidant, anticancer activities, and DNA/bovine serum albumin (BSA) binding studies. Based on the analytical… read more here.
Keywords: anticancer studies; thiophene; antioxidant anticancer; thiophene furan ... See more keywords
Synthesis of Phenanthro[9,10-c]thiophenes by 2,3-Dichloro-5,6-dicyano-1,4-benzoquinone (DDQ)-Promoted Cyclo-Oxidation.
Sign Up to like & getrecommendations! Published in 2019 at "ChemPlusChem"
DOI: 10.1002/cplu.201900099
Abstract: A new method to prepare phenanthro[9,10-c]thiophenes has been developed. In the presence of triflic acid, 3,4-diaryl thiophenes undergo 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ)-promoted cyclo-oxidation. NMR and computational studies indicate that protonation of the thiophene plays a key role… read more here.
Keywords: phenanthro thiophenes; cyclo oxidation; thiophene; dicyano benzoquinone ... See more keywords
Synthesis and antifungal activities of novel thiophene-based stilbene derivatives bearing an 1,3,4-oxadiazole unit.
Sign Up to like & getrecommendations! Published in 2019 at "Pest management science"
DOI: 10.1002/ps.5229
Abstract: BACKGROUND Natural stilbenes (especially resveratrol and its derivatives) are well-known phytoalexins that are active against many plant diseases. However, oxidative degradation and low bioavailability limit their exogenous application as fungicides on crops. In this study,… read more here.
Keywords: derivatives bearing; based stilbene; thiophene; thiophene based ... See more keywords
Design, cytotoxicity and toxicity of new thiophene and thieno [2,3-b] pyridine derivatives
Sign Up to like & getrecommendations! Published in 2017 at "Medicinal Chemistry Research"
DOI: 10.1007/s00044-017-1780-6
Abstract: Novel thiophene derivatives 3a–f were synthesized by using the 3-oxo-3-propanenitrile derivatives 1a–c with triethylamine, elemental sulfur and either of malononitrile or ethyl cyanoacetate. Compounds 3a, 3c, and 3e were reacted with ethyl cyanoacetate to give… read more here.
Keywords: thiophene; design cytotoxicity; cancer; thieno pyridine ... See more keywords
Uses of dimedone to synthesis pyrazole, isoxazole and thiophene derivatives with antiproliferative, tyrosine kinase and Pim-1 kinase inhibitions
Sign Up to like & getrecommendations! Published in 2020 at "Medicinal Chemistry Research"
DOI: 10.1007/s00044-020-02579-4
Abstract: We are aiming in this work to synthesize target molecules not only possess antitumor activities but also kinase inhibitors. The target molecules were obtained from dimedone, which reacted with triethoxymethane to produce a product that… read more here.
Keywords: pim kinase; kinase; thiophene; 14b 16b ... See more keywords
Physicochemical, optical and electrical investigation on poly [(phenylene-2-one)-co-(thiophene)] novel soluble conductive polymer as-synthesized through heterogeneous catalysis route
Sign Up to like & getrecommendations! Published in 2020 at "Polymer Bulletin"
DOI: 10.1007/s00289-020-03419-6
Abstract: Although the use of conductive polymers has invaded the electronics industry, the insolubility parameter presents a major problem against their direct application on the surfaces of materials. Attachment of cyclic compounds to polymer chains is… read more here.
Keywords: poly; thiophene; conductive polymer; spectroscopy ... See more keywords
Benchmarking semiempirical and DFT methods for the interaction of thiophene and diethyl sulfide molecules with a Ti(OH)4(H2O) cluster
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Molecular Modeling"
DOI: 10.1007/s00894-017-3392-y
Abstract: Semiempirical methods pm6 and pm7 as well as density functional theory functionals exchange LSDA, exchange-correlation PW91 and PBE, hybrid B3LYP1 and PBE0 were compared for energy and geometry of thiophene, diethyl sulfide (DES) molecules and… read more here.
Keywords: pbe0 31g; energy; thiophene diethyl; thiophene ... See more keywords
Concise synthesis and biological evaluation of 2-Aryl-3-Anilinobenzo[b]thiophene derivatives as potent apoptosis-inducing agents.
Sign Up to like & getrecommendations! Published in 2021 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2021.104919
Abstract: Many clinically used agents active in cancer chemotherapy exert their activity through the induction of cell death (apoptosis) by targeting microtubules, altering protein function or inhibiting DNA synthesis. The benzo[b]thiophene scaffold holds a pivotal place… read more here.
Keywords: apoptosis; thiophene; methoxybenzo; aryl ... See more keywords
Effective design of A-D-A small molecules for high performance organic solar cells via F atom substitution and thiophene bridge
Sign Up to like & getrecommendations! Published in 2019 at "Chinese Chemical Letters"
DOI: 10.1016/j.cclet.2019.07.018
Abstract: Abstract Three novel small molecules with acceptor-donor-acceptor (A-D-A) configuration, SBDT1 , SBDT2 and SBDT3 , where 4,8-bis(octyloxy)benzo[1,2-b:4,5-b']dithiophene (BDT) as the electron-donating core connecting to thiophene-substituted benzothiadiazole (BT) as electron-withdrawing are reported. The effects of fluorine… read more here.
Keywords: solar cells; thiophene; performance; organic solar ... See more keywords
Adsorption behavior of thiophene on MoS2 under a microwave electric field via DFT and MD studies
Sign Up to like & getrecommendations! Published in 2020 at "Chemical Engineering Science"
DOI: 10.1016/j.ces.2020.115950
Abstract: Abstract The adsorption behavior of sulfide over catalyst is the key to determine the desulfurization efficiency and its proceeding route. Molecular dynamics and density functional theory calculations were performed to provide theoretical insight into the… read more here.
Keywords: adsorption; field; thiophene; adsorption behavior ... See more keywords