Azathioprine-induced vanishing bile duct syndrome: the value of early thiopurine metabolism assessment.
Sign Up to like & getrecommendations! Published in 2023 at "British journal of clinical pharmacology"
DOI: 10.1111/bcp.15797
Abstract: About 15 to 28% of treated patients with thiopurines experienced adverse drug reactions, such as hematological and hepatic toxicities. A part of them is related to the polymorphic activity of the thiopurine S-methyltransferase (TPMT), the… read more here.
Keywords: duct; metabolism; azathioprine; blood ... See more keywords